Recommendations for selection of additives for stabilization of [F]FDG.

In this work, two relevant recommendations were established for selection of stabilizers for suppression of radiolysis of [F]FDG. First, the stabilizing effect could be enhanced using selective scavengers of hydroxyl radicals (OH). Additionally, the initial radiochemical purity could be retained due to compounds with rate constants of their reactions with OH (k) higher than 10 M s.

A Promising Future: Comparable Imaging Capability of MRI-Compatible Silicon Photomultiplier and Conventional Photosensor Preclinical PET Systems.

Unlabelled: We recently completed construction of a small-animal PET system-the MiniPET-3-that uses state-of-the-art silicon photomultiplier (SiPM) photosensors, making possible dual-modality imaging with MRI. In this article, we compare the MiniPET-3 with the MiniPET-2, a system with the same crystal geometry but conventional photomultiplier tubes (PMTs).

Methods: The standard measurements proposed by the National Electrical Manufacturers Association NU 4 protocols were performed on both systems.