Publications by authors named "Norbert Czumbel"
Background: Primary open-angle glaucoma (POAG), often associated with increased intraocular pressure (IOP), can lead to permanent damage of the optic nerve, concomitant visual field loss, and blindness. Latanoprost, a prostaglandin F2α analogue, reduces IOP and is used to treat glaucoma. In this clinical trial, we evaluated the efficacy of Latanoprost Polpharma, a generic preservative-free latanoprost 0.
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- The study aims to assess the effectiveness, safety, and immune response of a ranibizumab biosimilar (XSB-001) compared to the original product (Lucentis) in treating neovascular age-related macular degeneration (nAMD).
- It is a Phase III clinical trial involving 582 randomized patients who received either the biosimilar or the reference drug through intravitreal injections over a 52-week period.
- Results show that while XSB-001 led to a mean change in visual acuity of 4.6 ETDRS letters at 8 weeks, and 6.4 letters at 52 weeks, the differences from the reference product were within the predefined equivalence margin, indicating strong
Purpose: To evaluate the results of photorefractive keratectomy (PRK) and Laser in situ keratomieusis (LASIK) in eyes treated with hyperopia.
Patients And Methods: group 1 consisted of PRK-operated eyes, group 2 consisted of LASIK-operated eyes. In each group 20 eyes of 20 patients were listed.
Purpose: The aim of this pilot study was to determine the presence of complement activation products in tears from pre- and postkeratoplasty eyes and the fellow eyes in order to investigate the activation of the classical and alternative pathways of the complement system in the early postkeratoplasty period.
Methods: Tear samples from both eyes of 19 prekeratoplasty patients were tested. From 10 patients, samples were taken before operation, one week and 3 weeks after penetrating keratoplasty.
Aim Of The Study: To evaluate the results of laser in situ keratomileusis (LASIK) in groups with different refractive errors.
Patients And Methods: 68 LASIK procedure have been performed in the following patient groups: Group 1 (-3.0 D to -6.