Insulin resistance and risk of ischemic stroke among nondiabetic individuals from the northern Manhattan study.

Background: Whether insulin resistance predicts ischemic stroke (IS) is still a matter of debate.

Objective: To determine the association between insulin resistance (IR) and risk of first ischemic stroke in a large, multiethnic, stroke-free cohort without diabetes.

Design: Prospective, population-based cohort study.

Early depressed mood after stroke predicts long-term disability: the Northern Manhattan Stroke Study (NOMASS).

Background And Purpose: Depression is highly prevalent after stroke and may influence recovery. We aimed to determine whether depressed mood acutely after stroke predicts subsequent disability and mortality.

Methods: As part of the Northern Manhattan Stroke Study, a population-based incident stroke case follow-up study performed in a multiethnic urban population, participants were asked about depressed mood within 7 to 10 days after stroke.

Genetic contribution to brachial artery flow-mediated dilation: the Northern Manhattan Family Study.

Background: Brachial artery flow-mediated dilation (FMD) is a non-invasive measure of endothelial function. Endothelial dysfunction has been associated with traditional vascular risk factors and increased risk of cardiovascular disease. The importance of genetic contribution to FMD and baseline brachial artery diameter has not been shown in Hispanic populations.