Publications by authors named "Noratikah Mat Ail"
Article Synopsis
- Cyclotron production of Gallium-68 (Ga) radiopharmaceuticals is expanding, utilizing both solid and liquid targets, with this study focusing on the liquid target method's performance.
- The findings indicate that while the liquid target gives lower end-of-bombardment activity (4.48 GBq), extending irradiation time notably enhances the end-of-synthesis yield for specific radiopharmaceuticals, increasing activity from 1.33 GBq to 1.95 GBq for [Ga]Ga-PSMA-11.
- The study concludes that liquid target production is a viable method to produce Ga radiopharmaceuticals, capable of supplying up to 5 patients per production cycle while addressing encountered challenges and proposing potential solutions.
Designing and implementing various radionuclide production methods guarantees a sustainable supply, which is important for medical use. The use of medical cyclotrons for radiometal production can increase the availability of gallium-68 (Ga) radiopharmaceuticals. Although generators have greatly influenced the demand for Ga radiopharmaceuticals, the use of medical cyclotrons is currently being explored.
View Article and Find Full Text PDF