- The Truenat MTB Plus assay is a quick test for tuberculosis (TB) endorsed by the WHO since 2020, requiring further evaluation, especially for HIV-positive individuals and against the Xpert MTB/RIF assay.
- A study in Cameroon evaluated its diagnostic accuracy, involving 945 participants and comparing Truenat to Xpert using TB culture as a standard reference.
- Results showed that Truenat had similar sensitivity (91%) and specificity (96%) to Xpert, suggesting it is an effective option for TB detection, including in HIV-positive patients.