Solitary Keratoacanthoma of the Scalp: A Case Report.

Keratoacanthoma (KA) is a pruritic, rapidly growing cutaneous neoplasm originating from the infundibulum of the hair follicle on the sun-exposed area. Usually presents as a dome-shape with a centralized keratinous plug. Whether KA is benign or malignant is challenging due to its similarity to squamous cell carcinoma (SCC).

Emerging of composition variations of SARS-CoV-2 spike protein and human ACE2 contribute to the level of infection: approaches.

SARS-CoV-2 is causative of pandemic COVID-19. There is a sequence similarity between SARS-CoV-2 and SARS-CoV; however, SARS-CoV-2 RBDs (receptor-binding domain) binds 20-fold strongly with human angiotensin-converting enzyme 2 (hACE2) than SARS-CoV. The study aims to investigate protein-protein interactions (PPI) of hACE2 with SARS-CoV-2 RBD between wild and variants to detect the most influential interaction.