Allergic multimorbidity of asthma, rhinitis and eczema over 20 years in the German birth cohort MAS.

Background: The occurrence of allergic multimorbidity (coexistence of asthma, allergic rhinitis and eczema) has not been evaluated longitudinally from early childhood up to adulthood in a population-based study sample. We aimed to determine the prevalence of allergic multimorbidity up to age 20 stratified by parental allergies and sex/gender using extensive prospective follow-up data from two decades of a birth cohort study.

Methods: In 1990, we recruited 1314 healthy newborns from 6 maternity wards across Germany for the population-based MAS birth cohort study.

Early-life determinants of asthma from birth to age 20 years: a German birth cohort study.

Background: The lack of longitudinal data analyses from birth to adulthood is hampering long-term asthma prevention strategies.

Objective: We aimed to determine early-life predictors of asthma incidence up to age 20 years in a birth cohort study by applying time-to-event analysis.

Methods: In 1990, the Multicenter Allergy Study included 1314 newborns in 5 German cities.