Interval Timing as a Computational Pathway From Early Life Adversity to Affective Disorders.

Adverse early life experiences can have remarkably enduring negative consequences on mental health, with numerous, varied psychiatric conditions sharing this developmental origin. Yet, the mechanisms linking adverse experiences to these conditions remain poorly understood. Here, we draw on a principled model of interval timing to propose that statistically optimal adaptation of temporal representations to an unpredictable early life environment can produce key characteristics of anhedonia, a transdiagnostic symptom associated with affective disorders like depression and anxiety.

Overharvesting in human patch foraging reflects rational structure learning and adaptive planning.

Patch foraging presents a sequential decision-making problem widely studied across organisms-stay with a current option or leave it in search of a better alternative? Behavioral ecology has identified an optimal strategy for these decisions, but, across species, foragers systematically deviate from it, staying too long with an option or "overharvesting" relative to this optimum. Despite the ubiquity of this behavior, the mechanism underlying it remains unclear and an object of extensive investigation. Here, we address this gap by approaching foraging as both a decision-making and learning problem.