Publications by authors named "Nora A"

Acute suppurative thyroiditis (AST), a rare yet potentially life-threatening infection, comprises less than 1 % of neck pathologies and requires prompt treatment. Symptoms range from neck pain and fever to dysphagia and possible abscess formation. Broad-spectrum antibiotics are the primary treatment; however, surgical drainage may be necessary for abscesses to prevent systemic infection.

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This study aimed to investigate the association between bullying at school and tooth loss in southern Brazilian adolescents. This population-based cross-sectional study included a representative sample of 15-19-year-old students attending high schools in Santa Maria, southern Brazil. Data on sociodemographic and behavioral variables were collected through questionnaires.

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This study aimed to assess the association between underlying dentin shadows (UDS) and oral health-related quality of life (OHRQoL) among 15-19-year-old adolescents from southern Brazil. This population-based cross-sectional study included a representative sample of 1,197 15-19-year-old adolescents attending 31 public and private schools from Santa Maria, Brazil. The Oral Health Impact Profile-14 (OHIP-14) was used to evaluate the OHRQoL, and clinical examinations were performed by two calibrated examiners (intra/interexaminer kappa values for caries examination ≥ 0.

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In developmental language disorder (DLD), learning to comprehend and express oneself with spoken language is impaired, but the reason for this remains unknown. Using millisecond-scale magnetoencephalography recordings combined with machine learning models, we investigated whether the possible neural basis of this disruption lies in poor cortical tracking of speech. The stimuli were common spoken Finnish words (e.

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Article Synopsis
  • Lemierre syndrome is a rare but serious complication of throat infections, often affecting healthy young adults, and is caused by septic thrombophlebitis of the internal jugular vein.
  • The incidence of Lemierre syndrome is about 3.6 cases per million, with symptoms typically following a pharyngitis infection, leading to potential complications like pulmonary infections.
  • Early diagnosis through CT scans and prompt treatment with broad-spectrum antibiotics are crucial for preventing severe outcomes, as many patients can fully recover with the right therapy.
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  • COVID-19 is primarily known for causing respiratory issues, but recent studies have shown it can also lead to severe muscle inflammation (myositis) that could result in multi-organ failure and increased mortality.
  • Myositis in pediatric patients with COVID-19 was studied at Policlinico San Marco University Hospital, revealing symptoms like fever, calf muscle pain, and elevated serum creatine kinase (CK) levels in affected children.
  • Despite the potential severity, the majority of pediatric cases seemed to resolve without complications, highlighting the importance of monitoring specific markers for effective management and indicating the need for further research on the disease’s impact on muscles.
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Background: Implementation evaluations based on a hybrid deductive-inductive approach provide a detailed understanding of organizational choices to introduce and implement complex interventions and may help explain implementation success or failure. However, such evaluations may not be feasible due to resource constraints. Qualitative analyses of artifacts collected for other purposes during implementation may represent a cost-effective method to understand program implementation when robust evaluations are not feasible.

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  • Netherton syndrome is a rare genetic skin disorder marked by three main features: congenital ichthyosis (dry skin), immune system issues, and problems with the scalp.
  • A case study details a 1-month-old boy who experienced severe health challenges, including failure to thrive and feeding problems, as well as an abnormal high sodium level at birth.
  • The condition is caused by a mutation in the SPINK5 gene, leading to a protein deficiency that weakens the skin barrier, resulting in serious complications like skin infections and growth issues in infants.
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In the clinical practice, it is not common for pediatricians to visit children with overgrowth phenotype. When it happens, it is important to focus on the age of manifestations and research the pathogenic causes using appropriate genetic test. Cowden syndrome is one of these rare causes; it is an autosomal dominant genodermatosis characterized by multiple hamartomas of ectodermal, mesodermal, and endodermal origin.

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Background: Obesity is a prevalent chronic condition affecting children and adults worldwide, and it seems to influence the timing of tooth eruption. The aim of this study was to assess the as-sociation between weight status at age 12 and the eruption of permanent teeth at ages 12 and 14-15 among schoolchildren from southern Brazil.

Material And Methods: A cross-sectional survey was conducted in Porto Alegre, southern Brazil, and included a representative sample of 1,528 12-year-old schoolchildren.

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Article Synopsis
  • Klippel-Trenaunay syndrome is a rare congenital disorder defined by three main features: capillary malformations, varicosities, and tissue/bone hypertrophy, with diagnosis possible if at least two are present.
  • Capillary malformations are typically seen at birth, while varicosities and limb hypertrophy usually develop later, and while the syndrome is often benign, it can lead to serious complications in various organs.
  • Recent advancements categorize this syndrome under PIK3CA-related overgrowth spectrum disorders, with new insights into its genetic causes, clinical symptoms, potential complications, and management strategies for affected individuals.
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Objective: To assess the association between residence place, socioeconomic conditions and oral health-related quality of life (OHRQoL) among schoolchildren from southern Brazil.

Methods: Participants were 9-14-year-old schoolchildren from rural and urban municipal schools from Rosário do Sul, Brazil. The Child Perceptions Questionnaire (CPQ11-14) was used to assess OHRQoL.

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  • The study investigates the link between the electro-clinical patterns of epileptic spasms in infants and their underlying causes, categorizing cases into structural, genetic, infectious, metabolic, immune, and unknown etiology.
  • The research analyzed data from 104 patients aged 1 to 22 months, using video-EEG methods to observe differences in seizure types and their respective causes.
  • Results indicate specific patterns, like flexor spasms correlating with genetic causes and mixed spasms with structural causes, with distinct EEG features aiding in the classification of these conditions.
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Background And Objective: This study aimed to assess the prevalence, extent, risk indicators, and intraoral distribution of underlying dentin shadows (UDS) in the occlusal surfaces of the permanent posterior teeth.

Subjects And Methods: A total of 1197 adolescents were included in the study (participation rate of 72.3%).

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This study evaluated the efficacy of fluoride gel in arresting active non-cavitated caries lesions in permanent teeth. This randomized, triple-blind, placebo-controlled clinical trial randomized 100 schoolchildren aged 10.7 ± 2.

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Background: Guillain-Barrè syndrome (GBS) is an acute immune-mediated disorder affecting peripheral nerves and nerve roots with a variable clinical course and outcome. Epidemiologic analyses have revealed that the incidence of the syndrome increases linearly among the age. The clinical diagnosis of GBS is based on the family history, physical and neurological examination, electrodiagnostic exams, and cerebrospinal fluid analysis with the classical presence of albumin-cytologic dissociation.

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This study investigated the association between the city region and traumatic dental injury (TDI) among adolescents from Santa Maria, Rio Grande do Sul, Brazil. A population-based cross-sectional survey was conducted from March to November 2018, which included a representative sample of adolescents (15-19-year-old) attending public and private high schools. A questionnaire on sociodemographic information was sent to the parents/legal guardians of the selected adolescents.

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We reported the case of acute encephalopathy related to colonic acid treatment interruption in a 12-year-old female child presenting to our unit with episodes of vomiting, headache, irritability, acute confusional state, seizures, and left lower limb hypotonia. Brain magnetic resonance imaging (MRI) showed signs of vasogenic and cytotoxic edema at the cerebellar level bilaterally, and lesions at the temporo-occipito-parietal right level, temporomandibular left, and right thalamic with swelling of the convolutions and reduced differentiation between white and gray matter. The patient had suspended the folinic acid treatment at least 6 months before the present admission.

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Objective: To investigate the factors directly and indirectly associated with a cariogenic diet among southern Brazilian adolescents.

Materials And Methods: This cross-sectional study included 15-19-year-old students attending high schools in Santa Maria, southern Brazil. The participants completed a questionnaire on sociodemographic and behavioral variables.

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Objective: To investigate the clinical characteristics, the neuroimaging features and associated anomalies observed in children affected by Dandy-Walker malformations (DWM) and variants (DWV) in a single tertiary hospital in Catania and compare our data to their existent in the literature.

Methods: A retrospective case series using the medical records has been performed on 28 children diagnosed with DWM and DWV admitted to a single tertiary section of Pediatric Neurology, Department of Catania, Italy from January 2005 to January 2021. We reviewed the neuroimaging using the new diagnostic criteria of Klein et al.

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Background: Lower extremity amputations from diabetic foot ulcers (DFUs) are rebounding, and new biomarkers that predict wound healing are urgently needed. Anaerobic bacteria have been associated with persistent ulcers and may be a promising biomarker beyond currently recommended vascular assessments. It is unknown whether anaerobic markers are simply a downstream outcome of peripheral arterial disease (PAD) and ischemia, however.

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Objective: To characterize opportunities to postprescriptively modify antibiotic prescriptions initiated for treatment of suspected urinary tract infection (UTI) in nursing homes.

Design: Cross-sectional cohort study.

Methods: Data from the health records of residents treated for UTI between 2013 and 2014 in 5 Wisconsin nursing homes were abstracted using a structured approach.

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Diagnosis in children with physical and intellective anomalies is very challenging because of the wide spectrum of causes. Array-based comparative genomic hybridization (CGH) has acquired an important role in pediatric diagnostic work up. Interstitial deletion of the long arm of chromosome 12 are rare.

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