Publications by authors named "Nor Asma Ab Razak"

Article Synopsis
  • Breast cancer is the most common cancer among women, causing nearly 685,000 deaths in 2020, with epidermal growth factor receptors (EGFRs) linked to its development and treatment resistance.
  • EGFR has four homologues, and while gefitinib (GEF), a tyrosine kinase inhibitor for EGFR1, shows promise in treating breast cancer, clinical trials have not met expectations, highlighting a gap in understanding EGFR signaling.
  • Ongoing research into molecular pathways and the use of nanomedicines synthesized with GEF is crucial for improving treatment outcomes against breast cancer.
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Ethnopharmacological Relevance: The bulb of Eleutherine bulbosa (Mill.) Urb. is an indigenous medicinal plant traditionally used among Dayak people for the management of diabetes, breast cancer, hypertension, stroke, and fertility problems in women.

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The edible bird nest (EBN) from has been consumed as a Chinese traditional food for health and medicinal purposes due to its elevated nutritional value. The present study focused on the influence of characterization and extraction methods on protein profiling, which could be a guideline for grading the EBN. The proposed extraction method is similar to the common food preparation methods of consumers and thus can accurately establish the bioactive protein available upon human consumption.

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Calcium carbonate has slowly paved its way into the field of nanomaterial research due to its inherent properties: biocompatibility, pH-sensitivity, and slow biodegradability. In our efforts to synthesize calcium carbonate nanoparticles (CSCaCONP) from blood cockle shells (), we developed a simple method to synthesize CSCaCONP, and loaded them with gefitinib (GEF) and paclitaxel (PTXL) to produce mono drug-loaded GEF-CSCaCONP, PTXL-CSCaCONP, and dual drug-loaded GEF-PTXL-CSCaCONP without usage of toxic chemicals. Fourier-transform infrared spectroscopy (FTIR) results reveal that the drugs are bound to CSCaCONP.

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Edible bird's nest (EBN) produced by has a high demand for nutritional and medicinal application throughout the world. The present study was to evaluate the authentication of a man-made house EBN, which are half cup and stripe-shaped by FTIR. Next, both samples were compared according to their metabolite, nutritional, and mineral composition.

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Natural product is an excellent candidate for alternative medicine for disease management. The bulb of is one of the notable Iridaceae family with a variety therapeutic potential that is widely cultivated in Southeast Asia. The bulb has been used traditionally among the Dayak community as a folk medicine to treat several diseases like diabetes, breast cancer, nasal congestion, and fertility problems.

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