Estimation of Glyphosate biological half-life among farmers and residents in Thailand.

Glyphosate is a widely used herbicide worldwide. Research on human health effects has been limited and the toxicokinetics of glyphosate have not been widely examined. This research aimed to study the excretion profile and half-life of glyphosate in farmers and residents who use glyphosate to control weeds in their agricultural fields and near their households, respectively.

Exposure of Young Children to Permethrin and Cypermethrin Insecticides in the Residential Environment.

The aims of this study were to evaluate the exposure to permethrin and cypermethrin of young children aged between 2 and 5 years in Nakhon Pathom and Sing Buri provinces, Thailand. A questionnaire that included general demographic information, household characteristics, insecticide usage and exposure-related behavior in children was used to interview parents or family caregivers. Permethrin and cypermethrin concentrations on floor surfaces and children's hands, as well as their urinary metabolites, were analyzed by gas chromatography coupled with mass spectrometry.

Air, Dermal, and Urinary Metabolite Levels of Backpack and Tractor Sprayers Using the Herbicide Acetochlor in Thailand.

Acetochlor is a chloroacetanilide selective pre-emergent herbicide used for controlling grass and broadleaf weeds in crops. This study compared the acetochlor exposures of backpack and tractor sprayers and assessed whether dermal or air exposures were more important contributors to the overall body burden as measured by urinary metabolites. Sixty sugarcane farmers in Nakhonsawan province, Thailand participated in the study, and breathing zone air and dermal patch samples were collected during spraying.

Urinary Cypermethrin Metabolites among Conventional and Organic Farmers in Thailand.

Cypermethrin, a pyrethroid insecticide, is frequently spread on agricultural farmlands and is also used in households in Thailand. Conventional pesticide-using farmers ( = 209) were recruited from the Phitsanulok and Nakornsawan provinces. Certified organic farmers ( = 224) were also recruited in the Yasothorn province.

Pesticide residues on children's hands, home indoor surfaces, and drinking water among conventional and organic farmers in Thailand.

This study measured pesticide levels on children's hands, home indoor surfaces, and drinking water among Thai conventional and organic farm families in three provinces. Farm families in Nakhonsawan and Phitsanulok provinces were the conventional farmers and those in Yasothon province were the organic farmers. Samples were collected in the dry and wet seasons over 2 years (2017 and 2018).

Urinary Organophosphate Metabolites and Metabolic Biomarkers of Conventional and Organic Farmers in Thailand.

Organophosphate (OP) pesticides are used by most farmers to remove insects and to increase productivity; however, questions remain on the long-term health impacts of their use. This study assessed the relationship between OP biomarker levels and metabolic biomarker parameters. Conventional farmers ( = 213) and organic farmers ( = 225) were recruited, interviewed, and had physical health examinations.

Urinary glyphosate biomonitoring of sprayers in vegetable farm in Thailand.

In Thailand, glyphosate is popular herbicide to control pests in the agricultural sector. This study aimed to measure glyphosate exposure concentrations through inhalation, dermal contact, and urinary glyphosate concentrations among 43 vegetable farmers spraying glyphosate in Bungphra Subdistrict, Phitsanulok Province. Four types of spraying equipment were used, manual pump backpack ( = 3), motorized spray backpack ( = 22), battery pump backpack ( = 16), and high pressure pump ( = 2).

Occupational hazards, health conditions and personal protective equipment used among healthcare workers in hospitals, Thailand.

This cross-sectional study aimed to evaluate occupational hazards, health conditions and personal protective equipment used among healthcare workers. Information from the sample size of 1,128 healthcare workers were collected using questionnaires. The healthcare workers participated in this study were from five departments including inpatient, outpatient, surgery and anesthesia, nutrition service and hospital support services departments in five hospitals in Thailand.

Cross-shift change of acute kidney injury biomarkers in sugarcane farmers and cutters.

Sugarcane farmers and cutters have been reported to be at high risk of acute kidney injury. This cross-sectional study aimed to assess acute kidney injury biomarkers, and cross-shift change among 150 sugarcane cutters and 98 sugarcane farmers in Thailand. Physical health examination, environmental measurements, and measured urinary neutrophil gelatinase-associated lipocalin (NGAL) were assessed.

Pesticide use in Thailand: Current situation, health risks, and gaps in research and policy.

Agriculture in Thailand, which employs over 30 percent of the workforce and contributes significantly to the country's gross domestic product, is a key sector of its economy. Import and use of pesticides has increased over the past decade due to Thailand's major role as a leading exporter of food and agricultural products. The widespread and poorly regulated use of pesticides presents a potential risk to the health of farmers, farm families, the general population including children and the environment.

Factors Associated with Musculoskeletal Disorders Among Female Readymade Garment Workers in Bangladesh: A Comparative Study Between OSH Compliant and Non-Compliant Factories.

Purpose: Musculoskeletal Disorders (MSDs) are one of the most common occupational diseases responsible for work restriction and absenteeism. The purpose of the study was to compare the prevalence of MSDs between ready-made garment (RMG) factories that are compliant versus non-compliant with International Labor Organization (ILO) based Occupational Safety and Health (OSH) standards, and to identify other factors associated with a higher prevalence of MSDs.

Methods: A multicenter cross-sectional study was conducted among 410 randomly selected female workers (age: >18 years; ≥1 year of work experience) from 12 randomly selected RMG factories in the Dhaka district of Bangladesh from February to December 2019.

Disruption of the Diurnal Cortisol Hormone Pattern by Pesticide Use in a Longitudinal Study of Farmers in Thailand.

Alteration of the hypothalamic-pituitary-adrenal (HPA) axis hormones has been associated with a range of chronic metabolic and cardiovascular health conditions. This study evaluated whether type of farming (organic versus conventional) or the number of self-reported days of spraying pesticides in the past 8 months was associated with diurnal cortisol levels. Salivary cortisol levels were measured four times a day (waking, 30 min after waking, 6 h after waking and bedtime) longitudinally, 8 months apart during three rounds of data collection.

Acute Changes in Thyroid Hormone Levels among Thai Pesticide Sprayers.

The objective of this study was to investigate the relationship of acute pesticide exposures and acute changes in thyroid hormones among Thai farmers. We recruited 78 farmers, who were scheduled to spray insecticides (chlorpyrifos and/or cypermethrin) or herbicides (paraquat and/or glyphosate). On the day before spraying, farmers collected their first morning void urine and went for blood collection.

Longitudinal Study of Thyroid Hormones between Conventional and Organic Farmers in Thailand.

Many pesticides are endocrine-disrupting chemicals that can interfere with hormone levels. This study aimed to assess the longitudinal impact of exposure to pesticides on thyroid hormone levels, including Thyroid Stimulating Hormone (TSH), Free Triiodothyronine (FT3), Free Thyroxine (FT4), Triiodothyronine (T3), and Thyroxine (T4). Both conventional (i.

ORGANOPHOSPHATES IN MECONIUM OF NEWBORN BABIES WHOSE MOTHERS RESIDED IN AGRICULTURAL AREAS OF THAILAND.

Organophosphates (OPs) are widely used for pest and weed control in many countries including Thailand. In addition to causing environmental pollution, OPs affect human health by overstimulating neurotoxicants, and OP exposure during pregnancy can lead to adverse health effects of mothers and their fetuses. Using gas chromatography-mass spectrometry with a dedicated extraction protocol to identify OPs in meconium of newborn babies ( = 68) from hospitals in Amnat Charoen, Kanchanaburi and Nakhon Sawan provinces, agricultural regions of Thailand, among ten OP types analyzed, eight were detected in 98% of meconium samples (chlorpyrifos (median ± interquartile range (IQR) 0.

Longitudinal Study of Metabolic Biomarkers among Conventional and Organic Farmers in Thailand.

The aim of this longitudinal study is to assess how pesticide use may impact metabolic biomarkers by collecting and comparing data from conventional ( = 13) and organic farmers ( = 225) every eight months for four rounds. Farmers were interviewed about family health history, food consumption behaviors, self-reported health problems, agricultural activities, and history of pesticide use. Systolic and diastolic blood pressure and body mass index (BMI) were measured.

Paraquat exposure of backpack sprayers in agricultural area in Thailand.

Thai agriculturists heavily used paraquat in agricultural areas to control weed and grasses. This study determined paraquat exposure among backpack sprayers in Thailand and identified determinants of occupational exposure. Breathing zone air and dermal samples were collected from 57 backpack sprayers while spraying.

Thyroid Hormones in Conventional and Organic Farmers in Thailand.

Pesticides can act as endocrine disruptors by different mechanisms including inhibition of iodine absorption, increases in thyroid hormone clearance, decreased cellular uptake of thyroid hormones, or changes in expression of thyroid hormone regulated genes. This study examined how exposure to pesticides impacts thyroid hormone levels, thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), free T3 (FT3), and free T4 (FT4) by comparing conventional ( = 195) and organic farmers ( = 222), and by evaluating which types of pesticides might be associated with changes in thyroid hormone levels. Questionnaires were used to collect information about farmer characteristics, self-reported stress, agricultural activities, and history of pesticide use.

Hearing Loss in Agricultural Workers Exposed to Pesticides and Noise.

Agricultural workers who have concurrent exposure to pesticides and noise are at increased risk of hearing loss. We recruited 163 Thai conventional and 172 organic farmers to answer our questionnaires about personal demographics, agricultural activities, and pesticide and agricultural machinery use. This information was used to calculate the years of conventional (pesticide use) farming and the years of agricultural noise exposure, and to estimate semiquantitative metrics for pesticide exposure (cumulative intensity score-years) and cumulative noise exposure (dB(A)-years) for each conventional farmer.

Difference in Accidents, Health Symptoms, and Ergonomic Problems between Conventional Farmers Using Pesticides and Organic Farmers.

Organic farming has been promoted in Thailand by King Rama the ninth. In addition to being healthier for consumers, organic farming is healthier for agricultural workers. The cross-sectional study was conducted to investigate the frequency of chronic disease conditions, accidents, health symptoms, and ergonomic problems among 243 conventional (pesticide using) farmers and 235 organic farmers.

A Cross-Sectional Investigation of Cardiovascular and Metabolic Biomarkers among Conventional and Organic Farmers in Thailand.

Pesticide exposure has been implicated as a risk factor for developing a wide range of adverse health issues. Some examples are metabolic syndromes, including diabetes. This study investigated the relationship between current occupational use of pesticides and metabolic and cardiovascular biomarker levels among organic and conventional farmers in Thailand.

Evaluation of Dermal Exposure to the Herbicide Alachlor Among Vegetable Farmers in Thailand.

Vegetable farmers applying the herbicide alachlor may be highly exposed through dermal contact when spraying. Dermal patches were attached to 10 locations on the farmers' skin when they mixed and applied alachlor in vegetable farming areas in Thailand. Measurements were made on farmers using either a backpack sprayer with a 2 stroke gasoline motor and fan or a battery operated pump.

Paraquat Exposure of Pregnant Women and Neonates in Agricultural Areas in Thailand.

This study aimed to assess paraquat concentrations in the urine of women at 28 weeks of pregnancy, delivery and 2 months postpartum and in the meconium of neonates. In all, 79 pregnant women were recruited from three hospitals located in agricultural areas in Thailand. The subjects were interviewed about personal characteristics, agricultural activities and pesticide use patterns.

A pilot study of maternal exposure to organophosphate pesticides and newborn neurodevelopment in Thailand.

The objective of this study was to evaluate whether prenatal exposures to organophosphate (OP) pesticides from maternal agricultural use are associated with neonatal neurobehavioral effects. A pilot study conducted in three provinces in Thailand measured maternal urinary metabolites of OP pesticides in pregnant women at 7 months gestation and at birth. Within 3 days of birth, 82 newborns underwent neurobehavioral testing using the Brazelton Neonatal Behavioral Assessment Scale (NBAS).

Differences among Thai Agricultural Workers' Health, Working Conditions, and Pesticide Use by Farm Type.

More than 11 million Thai people (38%) work in agriculture, but since most are in the informal sector, government enforcement and support are very limited. As a result, working conditions on Thai farms vary greatly, putting the health of many agricultural workers at risk. A cross-sectional study in three Thai provinces collected information on the work activities and conditions of 424 farmers representing five farm types: rice, vegetable, flower, rice/vegetable, and flower/vegetable.