Publications by authors named "Nooshin Derakhshandeh"
Background: Dogs may be infected with species of Leishmania parasites that are disseminated through blood circulation and invade the internal organs. In this study, we aim to detect the parasite in the blood of dogs using the PCR technique. The present work was performed from February 2022 to May 2023 in Fars Province, southern Iran, where the disease is endemic.
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- Aromatase inhibitors, like letrozole, can enhance male fertility by altering hormone levels, specifically increasing testosterone while affecting estradiol levels in dogs.
- In a study with seven intact male dogs, letrozole administration led to a significant rise in testosterone levels after 14 days, while maintaining stable estradiol levels and reducing the estradiol:testosterone ratio.
- The treatment improved sperm viability and concentration after 28 days and also caused notable increases in prostate gland size, although sperm membrane integrity and movement parameters were not significantly impacted.
Background: Limited studies are available on vitamin D supplementation in dogs. This study evaluates the effect of a commercial vitamin D3 supplement on serum 25-hydroxy vitamin D as well as selected biochemical and hematological parameters in healthy dogs. Eight intact male adult dogs with a mean body weight of 20 kg from mixed breeds were included in the study.
View Article and Find Full Text PDFCanine hepatozoonosis is a tick-transmitted apicomplexan infection caused by two species of Hepatozoon, , and . The present research aimed at detection of Hepatozoon spp. in dogs and its effects on hematological alterations.
View Article and Find Full Text PDFUltrasonography is one of the most common methods for the diagnosis of prostate disorders, such as benign prostatic hyperplasia (BPH), in dogs. Changes in the echotexture are one of the indicators used to diagnose prostate disorders. The purpose of this study was to investigate the changes occurred in the dogs' prostate echotexture during the induction of BPH using image analysis.
View Article and Find Full Text PDFThe monitoring of serum prostatic biomarkers during the treatment will help clinicians to know the statement of the response to finasteride in dogs affected by benign prostatic hyperplasia (BPH). The present study was aimed to assess changes in the serum canine prostate-specific esterase (CPSE), prostate-specific antigen (PSA), prostatic acid phosphatase (PAP), testosterone, dihydrotestosterone (DHT) and prostate volume evaluation using ultrasonographic examination during the treatment with finasteride in BPH-induced dogs. Twenty dogs were divided into 4 groups (n = 5): BPH + finasteride group, dogs which were induced for BPH and received oral finasteride once daily for 1 month; BPH group, dogs which were induced for BPH and received placebo; finasteride group, normal dogs which received finasteride; and normal group, normal intact dogs which did not receive treatment.
View Article and Find Full Text PDFBackground: Prostatic hyperplasia (PH) is one of the most important disorders in intact dogs. In this study, we aimed to induce PH experimentally using the combination of testosterone and estrogen and evaluate important factors associated with this disease.
Results: The results showed that in the induction group, prostate volume and prostate specific antigen (PSA) concentration increased significantly on day 21 onwards compared to those of the control group.