Publications by authors named "Noorain Ahmad"
Diabetic nephropathy is becoming a more predominant cause of end-stage renal disease, as the prevalence of diabetes mellitus worldwide is on the rise. In this systematic review, we aimed to define the role of endothelin receptor antagonists, in the prevention and treatment of diabetic nephropathy, in addition to determining their safety. For this review, PubMed, Google Scholar, and Cochrane Library databases, in addition to ClinicalTrials.
View Article and Find Full Text PDFArticle Synopsis
- Systemic lupus erythematosus (SLE) can lead to under-diagnosis of macrophage activation syndrome (MAS), a severe complication; this systematic review aimed to identify triggers and mortality factors associated with MAS in SLE patients.
- A comprehensive search across multiple databases revealed eight studies highlighting key risk factors, including lupus flare, high SLEDAI scores, infections, medications, malignancy, and pregnancy that could precipitate MAS.
- MAS was linked to increased ICU admissions and mortality, with specific indicators such as elevated C-reactive protein (CRP) and altered liver function tests suggesting poor prognosis; the review noted limitations due to a lack of prospective studies and study variability, emphasizing the need for further research.