Publications by authors named "Noor Al-Rifai"
Article Synopsis
- Long-acting crystal suspensions of active pharmaceutical ingredients (API) involve a mixture of the API, water, and excipients to ensure a sustained release over time.
- PVP K30 was identified as the most effective excipient for stabilizing naproxen crystals, achieving a target crystal size of 1 to 15 μm by using ethanol and water in the process.
- A seven-stage diafiltration process successfully reduced the amount of PVP K30 present in the suspension without compromising crystal stability, demonstrating a significant decrease in the PVP-to-naproxen ratio.
