Both plants Sebastiania chamaelea from Niger and Chrozophora senegalensis from Senegal used in African traditional medicine in malaria treatment share a same active principle.

Ethnopharmacological Relevance: Based on ethnobotanical data obtained from Nigerien and Senegalese traditional healers, two Euphorbiaceae plants, Sebastiania chamaelea and Chrozophora senegalensis, traditionally used to treat malaria, were selected for further investigations.

Materials And Methods: Plant extracts were prepared with different solvents and tested both in vitro on several strains of Plasmodium falciparum, and in vivo to evaluate their antiplasmodial properties and isolate their active principles.

Results: With IC50 values around 6.

Evaluation of Senegalese plants used in malaria treatment: focus on Chrozophora senegalensis.

An ethnobotanical study was conducted in the Dakar area of Senegal to investigate the species used in the treatment of malaria. Seven plants are principally used: Cissampelos mucronata, Maytenus senegalensis, Terminalia macroptera, Bidens engleri, Ceratotheca sesamoides, Chrozophora senegalensis and Mitracarpus scaber. From a bibliographic study, it had been shown that the Cissampelos mucronata, Maytenus senegalensis and Terminalia macroptera have already been studied by several authors, and so only Bidens engleri, Ceratotheca sesamoides, Chrozophora senegalensis and Mitracarpus scaber were evaluated in the present study.

[Mechanisms of action of acetonic and hexanic extracts of leaves of Vernonia colorata (Willd.) Drake (Composeae) on blod glucose regulation].

Introduction: This study aimed to investigate the mechanism of action of acetonic and hexanic extracts of the leaves of Vernonia colorata on blood glucose regulation.

Materials And Methods: Experiments were performed in normoglycaemic, type 1 and 2 diabetic rats. The effects of acetonic and hexanic extracts on blood glucose were evaluated.

[Healing activity of methanolic extract of the barks of Spathodea campanulata Beauv (Bignoniaceae) in rat experimental burn model].

Spathodea campanulata Beauv. (Bignoniaceae) is widely distributed through Africa and found in particular in Cameroon and Senegal. It is used in traditional herbal medicine for the treatment of ulcers, filaria, gonorrhea, diarrhea and fever.

[Antidiabetic activity of the leaves of Vemonia colorata (Wilid.) Drake (Composees) in alloxan-induced diabetic rats].

Vemonia colorata is distributed through Africa (Benin, Cameroon, Senegal, Togo etc...

[Antipyretic effect of aqueous extract and alcaloid of Tinospora bakis (Miers) in rabbits].

Lyophilised aqueous extract and alcaloidic totum (basic form) from roots of Tinospora bakis (Miers) have been tested with hyperthermic rabbits by sub-cutaneous administration of Saccharomyces cerevisiae mixture at 2g/kg. Total aqueous extract had been orally administrated at three doses: 150, 300 and 600 mg/kg and we obtained significant antipyretic effects at 300 and 600 mg/kg. With the alcaloidic totum at 2.

Hypoglycaemic and antidiabetic activity of acetonic extract of Vernonia colorata leaves in normoglycaemic and alloxan-induced diabetic rats.

The aqueous extract of Vernonia colorata (Willd.) Drake (Composeae) leaves is used by African traditional medicine practitioners as a remedy for the treatment of diabetes. Our previous studies have shown the hypoglycaemic activity of the aqueous extract of Vernonia colorata leaves (300 mg/kg, per os) in normoglycaemic rats.

Phospholipid fatty acids and sterols of two Cinachyrella sponges from the Saudi Arabian Red Sea: comparison with Cinachyrella species from other origins.

Phospholipid class compositions, fatty acids and sterols of the sponges Cinachyrella alloclada and C. kükenthali from the Saudi Arabian Red Sea were studied and compared with previous results for other Cinachyrella spp. collected in Senegal (East Atlantic) and New Caledonia (West Pacific).