Publications by authors named "Nondumiso Premilla Dube"
BMC Complement Med Ther
September 2023
Article Synopsis
- - Stigmasterol, an unsaturated phytosterol found in Rhoicissus tridentata, exhibits a range of health benefits including anti-inflammatory, anti-cancer, and neuroprotective properties, making it a valuable compound for pharmacological applications
- - Researchers synthesized eight bio-active derivatives of stigmasterol through various chemical reactions, utilizing spectroscopic methods to confirm their structures and assess their cytotoxicity against specific breast cancer cell lines
- - The synthesized derivatives demonstrated enhanced cytotoxic activity compared to the original stigmasterol, with one derivative (5,6-Epoxystigmast-22-en-3β-ol) particularly showing promising results against the tested cancer cells
