Publications by authors named "Nondumiso P Dube"
Fatalities caused by infectious diseases (i.e., diseases caused by parasite, bacteria, and viruses) have become reinstated as a major public health threat globally.
View Article and Find Full Text PDFAdvances in Phytonanotechnology: A Plant-Mediated Green Synthesis of Metal Nanoparticles Using Plant Extracts and Their Antimicrobial and Anticancer Applications.
Nanomaterials (Basel)
September 2023
Nanoparticles and nanotechnology developments continue to advance the livelihood of humankind. However, health challenges due to microorganisms and cancerous cells continue to threaten many people's lives globally. Therefore, new technological interventions are of great importance.
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- - Stigmasterol, an unsaturated phytosterol found in Rhoicissus tridentata, exhibits a range of health benefits including anti-inflammatory, anti-cancer, and neuroprotective properties, making it a valuable compound for pharmacological applications
- - Researchers synthesized eight bio-active derivatives of stigmasterol through various chemical reactions, utilizing spectroscopic methods to confirm their structures and assess their cytotoxicity against specific breast cancer cell lines
- - The synthesized derivatives demonstrated enhanced cytotoxic activity compared to the original stigmasterol, with one derivative (5,6-Epoxystigmast-22-en-3β-ol) particularly showing promising results against the tested cancer cells
Species within the genus (Vitaceae) are commonly used in South African traditional medicine. The current review discusses the occurrence, distribution, traditional uses, phytochemistry, and pharmacological properties of species covering the period 1981-2020. The data reported were systematically collected, read, and analysed from scientific electronic databases including Scopus, Scifinder, Pubmed, and Google Scholar.
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