Biological and structural properties of graphene oxide/curcumin nanocomposite incorporated chitosan as a scaffold for wound healing application.

Aims: The purpose of this research is to fabricate chitosan (CS)/graphene oxide (GO)/curcumin (Cur) 3D scaffolds through the freeze-drying method for wound dressing applications.

Main Methods: GO is produced by Hammer's method; then, it is characterized by X-ray diffraction and TEM analysis. Fabricated scaffolds are characterized by FTIR, FESEM, AFM, water vapor transmission rate, PBS absorption, contact angle, tensile strength, porosity measurement, biodegradability, and drug release methods.

Electrospun poly-caprolactone/graphene oxide/quercetin nanofibrous scaffold for wound dressing: Evaluation of biological and structural properties.

Aims: In this study, for the first time, the effect of quercetin (Q) on the characteristic properties, antimicrobial activity, and cell viability of polycaprolactone (PCL)/graphene oxide (GO) electrospun scaffold was investigated.

Main Methods: Quercetin loaded graphene oxide nanoparticles have been incorporated into the poly-caprolactone solution, and their mixture has been electrospun to be applied as a nanofibrous scaffold for wound dressing and tissue engineering applications. The properties of scaffolds, like their morphology, tensile strength, hydrophilicity, and in vitro biological performance, are investigated.