Publications by authors named "Nomusa Christina Mzimela"

Article Synopsis
  • - The study highlights the rising prevalence of pre-diabetes in urban areas, particularly among individuals aged 25-45, and aims to explore immune response changes linked to the condition in Durban, South Africa.
  • - Blood samples from patients were categorized into non-diabetic, pre-diabetic, and type 2 diabetic groups, revealing increased eosinophil and basophil levels, as well as elevated serum inflammatory markers in pre-diabetic and diabetic patients compared to non-diabetics.
  • - The research indicates that pre-diabetes triggers immune activation, prompting calls for further studies with more diverse and larger sample sizes to better understand these immune responses based on gender representations.
View Article and Find Full Text PDF

: Pre-diabetes is an intermediate, asymptomatic state between normoglycaemia and the onset of type 2 diabetes mellitus (T2D). Recent reports indicate that there are sub-clinical changes observed in red blood cells during pre-diabetes. This systematic review protocol will provide an outline of all procedures in the synthesis of the available data on the changes in red blood cell indices.

View Article and Find Full Text PDF

Background: Pre-diabetes is an intermediate state between normoglycaemia and type 2 diabetes (T2D). This condition has been shown to be asymptomatic thus making it hard to investigate the changes that occur in the body during this state. Recent findings stipulate that in this state, there are changes that are often associated with T2D.

View Article and Find Full Text PDF

Background: Prediabetes is an asymptomatic, intermediate state between normoglycemia and the onset of type 2 diabetes mellitus. Recent reports indicate that during prediabetes, there are subclinical changes to immune cells and inflammatory markers. Therefore, this systematic review will provide a synthesis of the available data on the changes in the concentration of immune cells and selective inflammatory markers.

View Article and Find Full Text PDF
Article Synopsis
  • Pre-diabetes is a condition that signals an increased risk for developing diabetes and other metabolic issues, and this study aims to create a systematic review on its prevalence in South Africa.
  • The researchers will analyze various studies published from 2000 to 2020 to gather data on pre-diabetes rates and identify any factors that may contribute to differences in findings.
  • Since the study will use non-identifiable data, no ethics approval is needed, and the results are expected to enhance understanding of pre-diabetes in South Africa.
View Article and Find Full Text PDF

Pre-diabetes is a long-lasting condition that precedes type 2 diabetes (T2D). T2D has been shown to suppress the immune response. However, it remains unclear if immune activation occurs before the onset of T2D during the progression of the pre-diabetic state.

View Article and Find Full Text PDF