Publications by authors named "Nolan Baker"
Article Synopsis
- The budding yeast Saccharomyces cerevisiae's life cycle traits, like stable haploid clones and controllable mating, make it valuable for lab research.
- Research showed that natural isolates have diverse HO alleles, but limited diversity was found in North American oak isolates, indicating broad dispersal.
- A hands-on educational activity enabled students to isolate and identify wild yeast, fostering collaboration among different educational levels and showing adaptability for other regions.
Features of the natural life cycle of the budding yeast were crucial to its domestication as a laboratory experimental model, especially the ability to maintain stable haploid clones and cross them at will to combine alleles via meiosis. Stable haploidy results from mutations in , which encodes an endonuclease required for haploid-specific mating-type switching. Previous studies found an unexpected diversity of alleles among natural isolates within a small geographic area.
View Article and Find Full Text PDF