Publications by authors named "Nohuz E"

Introduction And Hypothesis: Various treatment options are currently available for the management of stress urinary incontinence (SUI). This study was aimed at determining the effectiveness and safety profile of Bulkamid, and identify predictive factors of clinical success.

Methods: This retrospective study conducted in two French urogynecology university centers between September 2019 and December 2023 included all patients with urinary incontinence who received Bulkamid.

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Article Synopsis
  • Laparoscopic cornuectomy is commonly used to remove Essure® implants, but there's a risk of the device fragmenting, which can complicate surgery.
  • A study of 66 patients by gynecologists assessed the effectiveness of intraoperative radiographs compared to direct inspection of the removed implants to check for any remaining fragments.
  • Results showed that while the sensitivity and specificity were high for both methods, senior gynecologists performed better than residents, and postoperative imaging is still advised for thorough checking after the procedure.
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Objective(s): Management and localisation strategies to remove nonpalpable contraceptive implants may be difficult. We aimed to evaluate our imaging modalities to identify deep implant and patient outcomes related to removal.

Study Design: In this retrospective study, we reviewed all cases referred to our specialised centre for nonpalpable contraceptive implants from January 2018 to August 2022.

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Objective: Sacrospinous fixation is the gold standard procedure for management of apical pelvic organ prolapse by the vaginal route. However, there may be a relevant risk of neurovascular injury due to the proximity of neurovascular structures. We propose an anatomical study concerning the sacrospinous ligament with a new innovative minimally invasive technology using both a suture capturing device and a chip-on-the-tip endoscope to perform sacropinous fixation.

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Objective(s): Many patients with Essure® implant may experience adverse events related to the device. Although local inflammation does not appear to be the pathophysiological mechanism underlying the symptoms, systemic inflammation could play a role. In the present study, as cytokines are involved in the inflammatory process, we proposed to investigate the profile of circulating and peritoneal cytokines.

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Purpose: The long-acting reversible contraception progestin subdermal implant (ENG implant) may be effective to improve endometriosis-related symptoms. Since adenomyosis is a histopathological form of endometriosis, we aimed to evaluate the effectiveness of ENG implant in adenomyosis management.

Materials And Methods: Electronic search in Medline, Scopus, Embase databases and Google Scholar using combinations of the following keywords: Progestin; subdermal implant; Implanon; Nexplanon; Adenomyosis; Endometriosis.

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Article Synopsis
  • Pelvic organ prolapse (POP) is a common issue in women, leading to the descent of pelvic organs, impacting quality of life, though it may not always cause symptoms.
  • Treatment options range from pelvic-floor physical therapy to surgical procedures like anterior sacrospinous ligament fixation (ASSLF), which has shown effectiveness, shorter operative time, and fewer complications compared to traditional methods.
  • A case study of a 72-year-old woman with advanced prolapse illustrates the importance of ASSLF, and a video tutorial has been developed to standardize and educate on the surgical steps involved, promoting better outcomes in treatment.
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The loss of apical support is usually present in patients with pelvic organ prolapse. An effective correction for the vaginal apex may be an essential part of a durable repair for these women. Apical suspension of the sacrospinous ligament is likely one of the best treatments by the vaginal route.

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Cystoceles are the most common prolapses. Limitation of the use of synthetic mesh has led to the comeback of native tissue repair procedures. We have developed a new transobturator technique with native tissue based on a mix of a vaginal plastron technique and the transobturator procedure.

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Article Synopsis
  • Essure® is a birth control device used by women from 2002 to 2018, but many women reported problems after getting it.
  • This study looked at how women felt after they had the Essure® removed, finding that many experienced improvement in their symptoms and quality of life.
  • Overall, after removal, most women felt better, but some still had issues, so it's important to weigh the pros and cons before making any decisions.
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Purpose: Many concerns have been raised about adverse effects related to Essure device. Several pathophysiological hypotheses have been proposed including allergic reactions, Autoimmune/Autoinflammatory Syndrome Induced by Adjuvants, galvanic corrosion with release of heavy metals and inflammation. In the present study, we aimed to focus on inflammation process by performing a histopathological evaluation of Fallopian tubes in symptomatic patients with Essure removal.

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Objective: Describe the "patient experience" regarding care provided during the surgical management of a loss of pregnancy in the first trimester and identify the factors influencing this experience.

Material And Methods: It is an observational prospective study conducted in two type III, academic, maternity wards in Lyon, France, carrying out 8,500 deliveries per year. Adult female patients, having undergone a suction curettage for a loss of pregnancy in the first trimester from 24 December 2020 to 13 June 2021 were inculded.

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Objective(s): The causal mechanistic relationships between Essure® and adverse effects are unclear, but corrosion in the in-vivo environment with release of metal ions may be suspected. Here we evaluated the concentrations of nickel (Ni), chromium (Cr) and tin (Sn) in the peritoneal fluid (PF) and in the fallopian tube (FT) during laparoscopic Essure® removal compared to a control group.

Study Design: Ni, Cr and Sn concentrations were determined in the PF and FT from two groups(group A: symptomatic patients with Essure®) vs group B (control group without Essure®) by Inductively Coupled Plasma Mass Spectrometry analysis.

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Background: Since health-related quality of life (HRQL) could improve after removal of Essure (Bayer, Leverkusen, Germany) inserts in symptomatic patients, we aimed to assess whether such postoperative enhancement was linked to the anatomic placement of the device.

Methods: Correct and incorrect placed Essure (Bayer) were identified in the electronic database of the French cohort Ablimco (cohort of consenting patients with laparoscopic Essure [Bayer] removal). HRQL, pain and heavy menstrual bleeding were evaluated after Essure (Bayer) removal with validated quality of life questionnaires (Short Form12 Questionnaire, Visual Analogue Scale, French version of the McGill Pain Questionnaire and the pictorial blood assessment chart PBAC).

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Nocardiosis is a rare opportunistic disease that primarily affects patients with deficient immune systems. is one of the rare species of Nocardia and it represents less than 3% of all Nocardia cases. Clinical presentation can be varied according to the affected organ.

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Article Synopsis
  • The COVID-19 pandemic led to significant changes in gynaecological cancer care, prompting a study to evaluate the psychological effects of these modifications on patients during the lockdown period in France.
  • In a study of 205 patients, treatment was maintained for 59.5%, delayed for 35.1%, and cancelled for 5.4%, with notable levels of anxiety (29.7% reported) and fatigue during the lockdown.
  • Post-lockdown, patients reported improved mental health scores, but those with delayed or cancelled treatments experienced higher anxiety levels, indicating that treatment changes had a lasting psychological impact.
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Purpose: To assess the level of stress and anxiety in healthcare workers in the departments of obstetrics and gynecology in France during and after the first Covid-19 lockdown.

Methods: Two web-based cross-sectional surveys using several validated questionnaires (the HAD scale, the PSS-10 questionnaire and the Short Form 12 Questionnaire [SF-12]) were proposed to all staff of obstetrics and gynecologic departments in 18 French university hospitals.

Results: A total of 1565 respondents answered the first questionnaire and 1109 completed the second survey.

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Objective: To evaluate the efficacy and safety of an endoscopic bag during laparoscopic morcellation of leiomyoma or myomatous uterus.

Materials And Methods: A total of 48 patients with symptomatic leiomyoma were randomized for laparoscopic morcellation in two groups: group A with a specific endoscopic bag or group B without any bag. The primary outcome measure was the detection of smooth muscle cells from washing after power morcellation determined by peritoneal cytology and immunohistochemistry (IHC).

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Since elytrocele/enterocele may occur between 0.1% to 10% after hysterectomy, surgical techniques to repair elytrocele should be learnt to master. We propose the step-by-step description of the vaginal technique: dissection and resection of the peritoneal sac followed by a mini-invasive posterior transvaginal sacrospinous colpopexy.

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Obstetrical anal sphincter injury (OASIS) may lead to significant comorbidities, including anal incontinence, rectovaginal fistula, and pain. A correct repair is required to avoid improper healing, as a persistent defect in the external anal sphincter after delivery can increase the risk of complications and worsening of symptoms following subsequent vaginal deliveries. Herein is described the surgical repair technique for a fourth degree perineal tear.

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The closure of port-sites wounds, as the ultimate step of surgical laparoscopic procedures, can be allowed by threads, staples, surgical glue or adhesive sutures. We describe a simple and easy skin suturing technique which saves time and provides significant surgical ergonomics.

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Ectopic pregnancy is a frequent and life-threatening risk of childbearing. Its management represents a mainstay of emergency gynecological surgery, and laparoscopy is the surgical gold standard technique. The technique of transvaginal natural orifice transluminal endoscopic surgery (V-NOTES) for the management of ectopic pregnancy is presented herein.

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