Publications by authors named "Nof E"
Article Synopsis
- The study focuses on the diagnostic process of Brugada syndrome (BrS) using ajmaline to expose the Type 1 Brugada pattern in patients, highlighting limited data on different populations.
- It analyzed 260 patients (average age 43.4, mostly males) who underwent ajmaline tests, revealing a significant number with syncope history and family backgrounds of BrS or sudden cardiac death.
- Results showed that less than half of the subjects met the current diagnostic criteria for BrS, but the overall rate of serious arrhythmia events was low over a median follow-up period of three years.
Article Synopsis
- * Analyzed outcomes between patients who received imaging and those who did not, finding no significant differences in complications, recurrence of atrial fibrillation, or re-hospitalization rates after one year.
- * Despite longer procedure times for those who underwent imaging (90 minutes vs. 74.5 minutes), the study concludes that pre-procedural imaging does not impact the safety or efficacy of PVI in managing atrial fibrillation.
Article Synopsis
- - The text discusses Calcium Release Deficiency Syndrome (CRDS), a serious genetic heart condition that can cause sudden cardiac arrest without clear reasons and is not detectable through standard tests.
- - The study aimed to analyze electrocardiogram (ECG) responses after brief periods of fast heart rates followed by pauses in order to develop a diagnostic test for CRDS.
- - Findings showed that patients with CRDS had a significantly greater change in T-wave amplitude on their ECG after a pause compared to control groups, indicating a potential diagnostic marker for this syndrome.
Article Synopsis
- Catheter ablation for atrial fibrillation (AF) is the most common procedure in electrophysiology, aiming to isolate pulmonary veins, but there is insufficient data on severe complications worldwide.
- A study involved collecting and analyzing data from 23 centers with 33,879 procedures to determine the incidence and management of severe complications during AF ablation.
- The study found that while severe complications like tamponade and stroke have a low incidence, factors like age, gender, and procedure duration play a role in their occurrence; most patients with complications were discharged after about 5 days.
Unlabelled: Aim To compare the 1-year survival rate of patients with atrial fibrillation (AF) following left atrial appendage occluder (LAAO) implantation vs. treatment with novel oral anticoagulants (NOACs).
Methods: We have conducted an indirect, retrospective comparison between LAAO and NOAC registries.
Article Synopsis
- The letter discusses strategies for enhancing clinical outcomes in patients suffering from tachycardia-induced cardiomyopathy.
- The authors, Dr. Naoya Kataoka and Dr. Teruhiko Imamura, emphasize the importance of timely diagnosis and effective management of this condition.
- They propose specific interventions and treatment approaches to optimize heart function and patient quality of life.
Article Synopsis
- Cardiac implantable electronic device (CIED) infections can manifest as either pocket or systemic infections, both requiring complete removal of the device and targeted antibiotic treatment.
- A study analyzed 300 patients and found that those with systemic infections presented more frequently with symptoms like leukocytosis and fever compared to those with isolated pocket infections.
- The study highlights a new category of "complicated pocket infection," suggesting that it should be recognized separately in future discussions of CIED infections due to its similar prognosis to isolated pocket infections despite presenting with more severe symptoms.
Even after a successful ventricular tachycardia ablation (VTA), some patients have recurrent ventricular tachycardia (VT) during their follow-up. We assessed the long-term predictors of recurrent VT after having a successful VTA. The patients who underwent a successful VTA (defined as the non-inducibility of any VT at the procedure's end) in 2014-2021 at our center in Israel were retrospectively analyzed.
View Article and Find Full Text PDFSurgical ablation for atrial fibrillation: impact of Diabetes Mellitus type 2.
Cardiovasc Diabetol
March 2023
Article Synopsis
- Diabetes type 2 is associated with higher health risks and complications in patients undergoing surgical ablation for atrial fibrillation (AF), particularly older age and higher rates of conditions like hypertension and stroke.
- A study involving 606 patients compared outcomes between non-diabetic and diabetic patients after AF ablation, revealing similar short-term AF recurrence and mortality rates within the first 3 years, but a notably higher 5-year mortality rate in diabetic patients.
- The findings suggest that while surgical ablation is effective for both groups, long-term outcomes may be less favorable for patients with diabetes type 2.
There exists an ongoing need to improve the validity and accuracy of computational fluid dynamics (CFD) simulations of turbulent airflows in the extra-thoracic and upper airways. Yet, a knowledge gap remains in providing experimentally-resolved 3D flow benchmarks with sufficient data density and completeness for useful comparison with widely-employed numerical schemes. Motivated by such shortcomings, the present work details to the best of our knowledge the first attempt to deliver in vitro-in silico correlations of 3D respiratory airflows in a generalized mouth-throat model and thereby assess the performance of Large Eddy Simulations (LES) and Reynolds-Averaged Numerical Simulations (RANS).
View Article and Find Full Text PDFBackground: data on the natural course and prognosis of tachycardia-induced cardiomyopathy (TICMP) and comparison with idiopathic dilated cardiomyopathies (IDCM) are scarce.
Objective: To compare the clinical presentation, comorbidities, and long-term outcomes of TICMP patients with IDCM patients.
Methods: a retrospective cohort study of patients hospitalized with new-onset TICMP or IDCM.
Article Synopsis
- The paper talks about how important it is to know the anatomy of the right ventricular outflow tract (RVOT) and how close it is to a blood vessel called the left anterior descending coronary artery (LAD) when treating heart rhythm problems.
- Between 2014 and 2017, five patients were found who had damage to the LAD during a heart procedure in three countries: Belgium, Germany, and Israel.
- The study suggests that doctors should be very careful when doing these procedures in that area, and using special imaging techniques could help prevent problems.
Article Synopsis
- * It involved 92 patients, with 84 undergoing DT; all successfully terminated induced ventricular fibrillation without complications, and follow-ups showed no inappropriate shocks or lead malfunctions.
- * The results indicated that while DT posed no complications, it did not yield any clinically significant findings for patient management.
Article Synopsis
- The study investigates patients with right bundle branch block (RBBB)-ventricular tachycardia (VT) and arrhythmogenic cardiomyopathy (ACM) by examining ECG characteristics of sinus rhythm (SR) and VT.
- It included 70 patients, revealing that the most common sites of origin for the VTs were primarily in the inferior and lateral walls of the left ventricle (LV), with a good correlation to electro-anatomic mapping (EAM) data.
- The findings highlight frequent abnormalities in SR depolarization and repolarization, which are associated with clinical implications in patients with ACM and RBBB-VT.
Background: Present guidelines endorse complete removal of cardiovascular implantable electronic devices (pacemakers/defibrillators), including extraction of all intracardiac electrodes, not only for systemic infections, but also for localized pocket infections.
Objectives: The authors evaluated the efficacy of delivering continuous, in situ-targeted, ultrahigh concentration of antibiotics (CITA) into the infected subcutaneous device pocket, obviating the need for device/lead extraction.
Methods: The CITA group consisted of 80 patients with pocket infection who were treated with CITA during 2007-2021.
(1) Background: Implantable cardioverter defibrillators (ICDs) have become the standard of care in the prevention of sudden cardiac death, yet studies have shown that competing causes of death may limit ICD benefits. The Norton scale is a pressure ulcer risk score shown to have prognostic value in other fields. The purpose of this study was to assess the use of the Norton scale as an aid for ICD patient selection; (2) Methods: The study was comprised of consecutive patients who underwent defibrillator implantation at Sheba Medical Center between 2008 and 2016.
View Article and Find Full Text PDFArticle Synopsis
- Ventricular tachycardia ablation (VTA) is challenging when patients have low blood pressure, but using veno-arterial extracorporeal membrane oxygenation (VA-ECMO) can help complete the procedure safely.
- A study gathered data from 46 patients who underwent VA-ECMO-assisted VTA, focusing on their medical history, procedure details, and outcomes, comparing those who were weaned off VA-ECMO immediately versus those who were not.
- Results showed that early de-cannulation from VA-ECMO was linked to significantly better survival rates after one year, highlighting the importance of timely weaning to reduce mortality risk.
Occluded vein as a predictor for complications in non-infectious transvenous lead extraction.
Front Cardiovasc Med
October 2022
Article Synopsis
- * Results show that patients with OV are older, have more comorbidities, lower ejection fractions, and longer lead dwelling times, leading to higher complications compared to those without occlusions.
- * The findings suggest that assessing for vein occlusion through venography before TLE can help identify patients at higher risk for complications and may require more complex extraction techniques.
QTc Dynamics Following Cardioversion for Persistent Atrial Fibrillation.
Front Cardiovasc Med
June 2022
Background: Cardioversion (CV) for atrial fibrillation (AF) is common. We aimed to assess changes in QTc over time following electrical CV (ECV) for persistent AF, and to compare the benefit of using continuous Holter monitoring vs. conventional follow-up by ECG.
View Article and Find Full Text PDFMortality rates among patients suffering from acute respiratory failure remain perplexingly high despite the maintenance of blood oxygen homeostasis during ventilatory support. The biotrauma hypothesis advocates that mechanical forces from invasive ventilation trigger immunological mediators that spread systemically. Yet, how these forces elicit an immune response remains unclear.
View Article and Find Full Text PDFIntroduction: Conflicting data exist on the prognostic significance of permanent pacemaker (PPM) implantation after transcatheter aortic valve replacement (TAVR).
Objective: The purpose of this study was to evaluate whether PPM implantation after TAVR is associated with adverse outcomes.
Methods: A retrospective analysis of a cohort comprised patients enrolled in a prospective registry between 2008 and 2019.
The past decade has witnessed tremendous endeavors to deliver novel preclinical lung models for pulmonary research endpoints, including foremost with the advent of and . With growing interest in aerosol transmission and infection of respiratory viruses within a host, most notably the SARS-CoV-2 virus amidst the global COVID-19 pandemic, the importance of crosstalk between the different lung regions (i.e.
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