Synopsis of recent research by authors named "Noemie Frezel"
- Noemie Frezel's research primarily focuses on the molecular and circuit mechanisms underlying neuropathic pain, with significant emphasis on the role of specific neuronal types, including c-Maf-positive spinal cord neurons and their contributions to sensory circuits in the dorsal horn.
- Frezel has also explored the implications of experimental methodologies in pain research, specifically investigating whether toe clipping in genetically modified mice affects their nociceptive responses later in life, highlighting the ethical considerations in animal research.
- In addition, Frezel has contributed to advancements in imaging techniques, such as light-sheet microscopy for studying cleared tissues, and has conducted detailed analyses on spinal nociceptive circuits using recombinant adeno-associated viruses, shedding light on the efficiency and specificity of gene transfer methods in neuroanatomical studies.