Publications by authors named "Noemie Celton"
A ZP1 gene mutation in a patient with empty follicle syndrome: A case report and literature review.
Eur J Obstet Gynecol Reprod Biol
January 2023
Article Synopsis
- Genuine empty follicle syndrome (gEFS) is a rare infertility issue where cumulus-oocyte complexes are present but no oocytes are found after IVF egg retrieval, linked to mutations in zona pellucida (ZP) proteins.
- A study focused on a 35-year-old woman diagnosed with gEFS revealed a new genetic variant in the ZP1 gene that likely disrupts protein assembly, explaining the absence of oocytes in her case after retrieval attempts.
- The findings suggest that genetic testing for ZP genes should be considered for similar infertility cases, allowing for better genetic counseling and potential treatment options like IVF adjustments or oocyte donation.
Cell-free DNA (Cf-DNA) fragments may constitute an easy-to-measure molecular tool for guiding the choice of care provided to infertile couples who benefit assisted reproductive technology (ART) programmes. Data on Cf-DNA levels in the seminal plasma of men with sperm alterations are scarce. The objective of the present study was to quantify the presence of Cf-DNA in semen by using a quantitative real-time PCR.
View Article and Find Full Text PDFA strong correlation between blastocyst morphology and implantation has been shown by many studies. The consequences and effects of assisted reproductive techniques on children's short and long-term health have always been a source of discussion. The obstetric and perinatal outcome of singletons according to blastocyst morphology has rarely been evaluated.
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