Response to Ovarian Stimulation for Urgent Fertility Preservation before Gonadotoxic Treatment in -Pathogenic-Variant-Positive Breast Cancer Patients.

pathogenic variants increase the risk of developing early and aggressive breast cancers (BC). For these patients, fertility potential can be directly affected by oncologic treatments. In addition, evidence indicates that -mutated women had a significant reduction in their ovarian reserve.

Disease-free survival does not differ according to fertility preservation technique for young women with breast cancer.

Objective: To study whether fertility preservation strategies using ovarian stimulation or without using it impact long-term disease-free survival of patients with breast cancer.

Design: Retrospective bicentric cohort study.

Setting: Two university hospitals.

[Prognostic assessment and treatment of early breast cancer].

Prognostic assessment and treatment of early breast cancer. Breast cancer is the most common cancer occurring in France and worldwide. In 2017 it has been estimated that 59.