Publications by authors named "Noelia Cubino-Boveda"
Anti-signal recognition particle myopathy (anti-SRP myopathy) is a rare subtype of immune-mediated inflammatory myopathy characterized by muscle weakness and anti-SRP autoantibodies. Although plasma exchange (PE) is used in severe cases, its role remains unclear. A systematic review was conducted following PRISMA guidelines, identifying 23 patients with anti-SRP myopathy treated with PE.
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- The study developed a machine-learning model to predict which hospitalized Covid-19 patients are at higher risk for severe disease, using clinical and lab data from patient admissions.
- The model was trained on 918 patients, validated internally, and then tested on 352 patients from a different hospital, achieving strong accuracy rates (AUC of 0.85 and 0.83, respectively).
- Key predictive factors included blood oxygen levels, age, kidney function, and various inflammatory markers, and the model is now available as an open-source tool for risk assessment.