Introduction: The incidence of inflammatory bowel disease (IBD) is increasing worldwide.
Objectives: To evaluate the incidence of IBD in Castilla y León describing clinical characteristics of the patients at diagnosis, the type of treatment received and their clinical course during the first year.
Materials And Methods: Prospective, multicenter and population-based incidence cohort study.
Background: There is limited evidence on the effectiveness of biological therapy in stricturing complications in patients with Crohn's disease.
Aim: The study aims to determine the effectiveness of anti-tumor necrosis factor (TNF) agents in Crohn's disease complicated with symptomatic strictures.
Methods: In this multicentric and retrospective study, we included adult patients with symptomatic stricturing Crohn's disease receiving their first anti-TNF therapy, with no previous history of biological, endoscopic or surgical therapy.