The impact of the intensity of media use on potential tourists' risk perception and travel protective behavioral intentions in COVID-19.

Introduction: In light of the COVID-19 pandemic, there is an increased need for potential travelers to gather information about their trips to mitigate perceived risks. This study aims to understand the relationship between the intensity of media use (both new and traditional), epidemic risk perception, and tourism protection behavior intention among potential tourists.

Methods: A total of 491 valid questionnaires were collected in Shanghai, China.

Simulated large joint fluid model for evaluating intra-articular antibiotic delivery systems: initial evaluation using antibiotic-loaded calcium sulfate beads.

: Local antimicrobial delivery via calcium sulfate (CaSO ) beads is used as an adjunctive treatment for periprosthetic joint infection. There is limited clinical information describing the performance of antimicrobial-loaded CaSO (ALCS) in large-scale applications. We developed a simulated large joint model to study properties of eluting ALCS.

Restoration of Visitors through Nature-Based Tourism: A Systematic Review, Conceptual Framework, and Future Research Directions.

Visiting natural environments could restore health and contribute to human sustainability. However, the understanding of potential linkages between restoration of visitors and nature-based tourism remains incomplete, resulting in a lack of orientation for researchers and managers. This study aimed to explore how visitors achieve restoration through nature by analyzing published literature on tourism.

The Experience of Novelty and the Novelty of Experience.

In cognitive psychology novelty is an antecedent of attention, emotion, memory, and behavior. However, the relationship between novelty and experience memorability remains conceptually underdeveloped in tourism. This research applies cognitive appraisal theory (CAT) to explore the contribution of novelty and emotion to memorable tourism experiences (MTEs).

Locally Delivered Nonsteroidal Antiinflammatory Drug: A Potential Option for Heterotopic Ossification Prevention.

Oral nonsteroidal antiinflammatory drugs (NSAIDs) are prescribed for heterotopic ossification prophylaxis following at-risk injuries and procedures. We hypothesized that NSAIDs may be delivered locally in a wound for heterotopic ossification prophylaxis. In in vitro work, we cultured osteoblasts with three commercially available NSAIDs and then measured cell viability and DNA content.

Local antibiotic delivery using tailorable chitosan sponges: the future of infection control?

Objectives: Local antibiotic delivery is a viable and attractive option for preventing infection. Unfortunately, the current options are limited and often necessitate surgical removal. This study evaluates the ability of a biodegradable and biocompatible chitosan sponge to minimize infection by delivering local antibiotics within the wound.

Chitosan sponges to locally deliver amikacin and vancomycin: a pilot in vitro evaluation.

Background: Open orthopaedic wounds are ideal sites for infection. Preventing infection in these wounds is critical for reducing patient morbidity and mortality, controlling antimicrobial resistance and lowering the cost of treatment. Localized drug delivery has the potential to overcome the challenges associated with traditional systemic dosing.

Chitosan films: a potential local drug delivery system for antibiotics.

Local antibiotic delivery is an emerging area of study designed to provide alternative methods of treatment to clinicians for compromised wound sites where avascular zones can prevent the delivery of antibiotics to the infected tissue. Antibiotic-loaded bone cement is the gold standard for drug-eluting local delivery devices but is not ideal because it requires a removal surgery. Chitosan is a biocompatible, biodegradable polymer that has been used in several different drug delivery applications.