Publications by authors named "Noel C Ales"
Although the Geneva protocol that prohibits the use of chemical and biologic weapons was ratified in 1925, many countries failed to accept this protocol: others stipulated retaliation, and some, like the United States, did not ratify the protocol for decades. This delay allowed the continued development of chemical and biologic agents. Members of the health care community are responsible for determining the best way to protect society from the potentially devastating effects of these biologic agents.
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- A study was conducted to investigate lung injuries linked to fludarabine therapy, aiming to create a case definition, guide management options, and pinpoint risk factors for pulmonary toxicity.
- Out of 105 patients treated with fludarabine, 8.6% experienced pulmonary toxicity, characterized by symptoms like dyspnea and radiographic changes, while maintaining exclusions for infections and disease progression.
- The findings suggested that corticosteroids were effective in managing symptoms, although one patient died of an infection during treatment, and a repeat administration of fludarabine triggered similar lung issues in another patient.