Publications by authors named "Nodoka Kouzen"
Article Synopsis
- The study aimed to evaluate the effectiveness of desmopressin orally disintegrating tablets (ODT) in reducing nighttime urination (nocturia) in male patients while analyzing factors that predict improvements.
- Conducted at 27 institutions in Japan, the research included 118 male patients and found a persistence rate of about 51.3% after 12 weeks, with many discontinuing treatment due to adverse events, primarily hyponatremia.
- Results showed significant reductions in nighttime frequency of urination, particularly for patients with larger nighttime urine volumes, indicating that desmopressin ODT is useful for male patients with nocturnal polyuria in real-world settings.
Effective management of immune-related adverse events in patients receiving immunotherapy for cancer is problematic. In this report, we present the case of a 58-year-old man with advanced clear cell renal cell carcinoma who responded well to a combination of ipilimumab and nivolumab. However, after two courses of treatment, he developed fulminant hepatitis and died.
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