Publications by authors named "Nocent-Ejnaini C"
Background: Chronic obstructive pulmonary disease (COPD) is a common treatable disease often diagnosed in patients with risk factors after a prolonged period with suggestive symptoms. Our qualitative study aimed to identify barriers to establishing diagnosis in the natural history of this condition.
Methods: An inductive thematic analysis was performed on structured interviews with patients, general practitioners (GPs) and pulmonologists in France.
Article Synopsis
- A study found that about 21.9% of patients hospitalized with severe COPD exacerbations were undiagnosed, indicating a consistent issue over the years 2017-2022.
- Factors linked to underdiagnosis included a higher forced expiratory volume (FEV) and being female, suggesting these groups need more attention in diagnosis efforts.
- Importantly, although undiagnosed patients had lower rates of rehospitalization and mortality, those who did have exacerbations faced higher mortality correlated with age and comorbidity, underscoring the importance of proper diagnosis and treatment.
Purpose: Pulmonary rehabilitation (PR) is a type of multidisciplinary care strongly recommended after severe exacerbation of chronic obstructive pulmonary disease (COPD). Recently, a national French study reported a very low rate of PR uptake (8.6%); however, important clinical data were missing.
View Article and Find Full Text PDFBackground: Biological therapies have revolutionized the treatment of severe asthma with type 2 inflammation. Although such treatments are very effective in reducing exacerbation and the dose of oral steroids, little is known about the persistence of symptoms in severe asthma patients treated with biologics.
Purpose: We aim to describe asthma control and healthcare consumption of severe asthma patients treated with biologics.
Article Synopsis
- A study in France, called the SISCOVID study, looked at lung health in patients who recovered from COVID-19 three and six months after being discharged from the hospital.
- Of the 320 patients assessed, many faced ongoing breathing issues and lung function problems, with those who had severe COVID-19 experiencing more significant complications.
- The findings indicate that over half of the patients had persistent dyspnoea and lung impairment at six months, highlighting the importance of ongoing monitoring and research into the long-term effects of COVID-19 on lung health.
Background: Obstructive sleep apnoea syndrome (OSAS) and severe asthma are frequently associated. This article focuses on the relationship between severe asthma phenotypes and OSAS.
Methods: FASE-CPHG was an observational, cross-sectional, prospective, multicentric study conducted in 104 non-academic hospitals from May-16 to July-17.
Introduction: Data on severe asthma in France are scarce. The aim of this study was to evaluate adherence to asthma treatments and its determinants in a population of severe asthmatics.
Methods: From May 2016 to June 2017, the French Collège des Pneumologues des Hôpitaux Généraux organized a large-scale prospective, cross-sectional, multicenter study on this topic; 1502 patients with severe asthma were included.
Introduction And Objective: Dyspnoea is a major symptom in COPD patients, but the determinants that could be associated with a higher dyspnoea mMRC score in COPD patients remain unclear. Our research aimed to study the determinants of dyspnoea at the threshold of 1, 2, 3 and 4 mMRC.
Patients And Methods: Diagnosis of COPD was made using spirometry with post-bronchodilator FEVFVC<70%.
Introduction: Exacerbations are key events in the natural history of COPD, but our understanding of their longitudinal determinants remains unclear. We used data from a large observational study to test the hypothesis that vaccination status and comorbidities could be associated with the occurrence of exacerbations profile.
Methods: Diagnosed COPD patients have been included by their pulmonologists, with up to 3 years of follow-up.
Introduction: Data on physical activity in severe asthma are scarce. From May 2016 to June 2017, 1502 adult patients with severe asthma visiting a pulmonologist practicing in one of the 104 non-academic hospitals participating in the study were included in this prospective, cross-sectional, multicenter study, provided they gave consent. Physical activity was classified according to 4 levels: 1 (no activity), 2 (occasional), 3 (regular), or 4 (frequent).
View Article and Find Full Text PDFIn a woman's life, asthma can affect her in a variety of ways, with the onset of premenstrual asthma currently under-diagnosed. It is estimated that about 20% of women with asthma have premenstrual asthma, which is more common in patients with severe asthma. Women with asthma are at high risk of exacerbations and of severe asthma.
View Article and Find Full Text PDFBackground: Real-world data describing management of patients with severe asthma are limited. To address this issue, we conducted FASE-CPHG (France Asthme Sevère - Collège des Pneumologues des Hôpitaux Généraux), a descriptive, multicentric, and observational cross-sectional study.
Methods: French pulmonologists from nonacademic hospitals completed questionnaires on patient characteristics and ongoing asthma treatment for severe asthmatic patients observed during the inclusion period.
Background: The impact of COPD on patient's quality of life is well established, but gender differences have received little attention.
Methods: To describe factors associated with the health-related quality of life by gender: A cross-sectional observational study (NCT01007734) was conducted in COPD patients followed by pulmonologists. The first patient included had to be a woman.
Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a disorder resulting from an interaction between a genetic predisposition, still poorly understood, and the impact of environmental factors including tobacco smoke or professional or domestic air contaminants.
Background: The prevalence of COPD in the world concerns women as much as men, but it remains under diagnosed among women smokers. The mortality data show an increase in mortality among women compared to men.
Introduction: The level of a patient's knowledge about his disease and its treatment is an essential part of an educational assessment. It is useful therefore to make use of a rapid, easy and valid method to collect the information necessary to develop an educational programme adapted to the needs of the patient. The aim of this study is to validate, in a structured way, a knowledge questionnaire on chronic obstructive pulmonary disease (COPD).
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