Ex-vivo expanded CD34 cell transplantation alleviates fibrotic liver injury via innate immune modulation in metabolic dysfunction-associated steatohepatitis mice.

Background: In drug-induced liver injury, vascular endothelial progenitor cells, specifically the CD34 cell fractions, have been found to decrease liver fibrosis and promote regeneration. However, it is unclear whether CD34 cell transplantation has anti-fibrogenic effects on MASH, which has previously been treated effectively with anti-angiogenic therapy. We investigated the efficacy of ex vivo-expanded CD34 cells in treating MASH livers.

Differences in apparent diffusion coefficients between normal brain echo-planar images and turbo spin-echo diffusion-weighted images with distortion correction.

Purpose: We performed echo-planar imaging (EPI) and turbo spin-echo (TSE) diffusion-weighted imaging (DWI) using magnetic resonance imaging (MRI) to obtain basic clinical data of the apparent diffusion coefficient (ADC) in various parts of normal brains and compared the datasets using our retrospective distortion correction technique.

Materials And Methods: The normal brains of 32 patients who underwent health check were scanned on a 1.5-T MRI instrument using EPI- and TSE-DWI.

Intraosseous metaplastic meningioma: A case report.

Metaplastic meningioma is a rare World Health Organization Grade I meningioma subtype, accounting for 0.2%-1.6% of all meningiomas.

Hydrocephalus Resulting from Late-Onset Aqueductal Membranous Occlusion: A Case Report and Review of the Literature.

Background: Late-onset aqueductal membranous occlusion (LAMO) is 1 of the few causes of noncommunicating hydrocephalus. Here, we report a case of LAMO and review the associated literature.

Case Description: A 36-year-old man had complained of headache and loss of consciousness.

Analyses of sizable ZFS and magnetic tensors of high spin metallocomplexes.

The fictitious spin-1/2 Hamiltonian approach is the putative method to analyze the fine-structure/hyperfine ESR spectra of high spin metallocomplexes having sizable zerofield splitting (ZFS), thus giving salient principal g-values far from around g = 2 without explicitly providing their ZFS parameters in most cases. Indeed, the significant departure of the g-values from g = 2 is indicative of the occurrence of their high spin states, but naturally they never agree with true g-values acquired by quantum chemical calculations such as sophisticated DFT or ab initio MO calculations. In this work, we propose facile approaches to determine the magnetic tensors of high spin metallocomplexes having sizable ZFS, instead of performing advanced high-field/high-frequency ESR spectroscopy.

Comparative Study for Alignment of Extramedullary Guides versus Portable, Accelerometer-Based Navigation in Total Knee Arthroplasty.

The use of portable, accelerometer-based navigation (PN) devices for positioning of the components of total knee arthroplasty (TKA) is emerging as an alternative to standard extramedullary (EM) systems, which was needed to the image intensifier. The aim of our study was to compare the accuracy of component positioning in TKA using an EM and PN systems. Data from 100 consecutive primary TKAs, performed by multiple surgeons in 87 patients between October 2010 and June 2015, were analyzed.

Posterior Reversible Encephalopathy Syndrome with Extensive Deep White Matter Lesions Including the Temporal Pole.

Posterior reversible encephalopathy syndrome (PRES) typically affects the posterior subcortical white matter. We report the case of a 55-year-old man with atypical PRES, who had malignant hypertension and renal dysfunction. Magnetic resonance imaging of the brain revealed extensive vasogenic edema in the deep white matter including the temporal pole, as well as in the brainstem and cerebellum.

Accuracy of a novel extramedullary femoral alignment guide system in primary total knee arthroplasty.

Introduction: We aimed to assess the accuracy of a new extramedullary guide system for achieving appropriate femoral component alignment in total knee arthroplasty (TKA) and to determine whether it differed between patients operated on by different surgeons.

Materials And Methods: We performed 100 consecutive primary TKAs in 100 patients using a newly developed extramedullary guide, the "S guide"; 50 were performed by author KM at A Hospital, and 50 by author NM at B Hospital. All patients received the Vanguard RP mobile-bearing prosthesis (Biomet Japan, Tokyo, Japan).

In vivo kinematics of a low contact stress rotating platform total knee arthroplasty system under weight bearing and non-weight bearing condition.

Background: The patterns and magnitudes of axial femorotibial rotation are variable due to the prosthesis design, ligamentous balancing, and surgical procedures. We aimed to investigate the effects of the weight bearing (WB) condition on the kinematics of mobile-bearing total knee arthroplasty (TKA).

Methods: We examined 12 patients (19 knees) implanted with a low contact stress (LCS) mobile-bearing TKA system using a two-dimensional to three-dimensional registration technique.

MRI of the cervical nerve roots in the diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy: a single-institution, retrospective case-control study.

Objective: To systematically evaluate the usefulness of assessing the cervical nerve roots by MRI for the diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).

Design: Single-institution, retrospective case-control study.

Setting: A regional referral hospital.

A synthetic two-spin quantum bit: g-engineered exchange-coupled biradical designed for controlled-NOT gate operations.

A quantum gate: A system of two coupled electron spins that is useful for simple quantum computing operations has been prepared by synthesis of a biradical 1 and co-crystallization with an isomorphous host molecule. The two weakly exchange-coupled quantum bits (target qubit blue and control qubit red) span four electron spin states. The electron spin transition is denoted by two black arrows.

Anterior temporal lobe white matter abnormal signal (ATLAS) as an indicator of seizure focus laterality in temporal lobe epilepsy: comparison of double inversion recovery, FLAIR and T2W MR imaging.

Objectives: To investigate the diagnostic capability of anterior temporal lobe white matter abnormal signal (ATLAS) for determining seizure focus laterality in temporal lobe epilepsy (TLE) by comparing different MR sequences.

Methods: This prospective study was approved by the institutional review board and written informed consent was obtained. Three 3D sequences (double inversion recovery (DIR), fluid-attenuated inversion recovery (FLAIR) and T2-weighted imaging (T2WI)) and two 2D sequences (FLAIR and T2WI) were acquired at 3 T.

Differential aquaporin 4 expression during edema build-up and resolution phases of brain inflammation.

Background: Vasogenic edema dynamically accumulates in many brain disorders associated with brain inflammation, with the critical step of edema exacerbation feared in patient care. Water entrance through blood-brain barrier (BBB) opening is thought to have a role in edema formation. Nevertheless, the mechanisms of edema resolution remain poorly understood.

Hyperintense dentate nucleus on unenhanced T1-weighted MR images is associated with a history of brain irradiation.

Purpose: To assess the frequency of hyperintensity in the dentate nucleus on T1-weighted magnetic resonance (MR) images and to establish correlations between such hyperintensity and clinical factors, including a history of brain irradiation.

Materials And Methods: This study was approved by the institutional review board, and each patient provided written informed consent. Three hundred sixty-two patients (164 men, 198 women; mean age, 62 years) were evaluated.

Two-stage revision surgery for hip prosthesis infection using antibiotic-loaded porous hydroxyapatite blocks.

Background: Infection of a hip prosthesis is one of the most severe complications encountered in orthopedic practice. Two-stage reconstruction using an antibiotic-impregnated cement spacer has become a popular procedure for the treatment of this condition. However, there are some disadvantages with the use of antibiotic-loaded cement, including low biocompatibility, a very low release ratio, and the possibility of thermal damage to the antibiotic.

Cementless total hip arthroplasty using a spongy metal surface hip prosthesis with a collarless, proximally porous-coated stem.

A collarless, proximally porous-coated type of Spongiosa Metal II hip prosthesis was used for cementless total hip arthroplasty in 52 hips, and 48 hips were followed and assessed during a mean follow-up period of 6.3 years (minimum 5 years). There were 8 hips (16.

Susceptibility-weighted imaging at 3 Tesla delineates the optic radiation.

Objectives: Some white matter tracts, including the optic radiation (OR), have recently been reported to be delineated as low signal intensity bands (LSBs) on T2*-weighted images at 7 T, presumably because of susceptibility effects caused by myelin.Susceptibility-weighted imaging (SWI) is more sensitive to magnetic susceptibility than T2*-weighted imaging. This study examined whether the LSBs, lateral to the lateral ventricles (LVs) on 3-T SWI, represent the OR.

Gray matter-white matter contrast on spin-echo T1-weighted images at 3 T and 1.5 T: a quantitative comparison study.

Discrepancies exist in the literature regarding contrast between gray and white matter on spin-echo (SE) T1-weighted MR imaging at 3 T. The present study quantitatively assessed differences in gray matter-white matter contrast on both single- and multi-slice SE T1-weighted imaging between 3 and 1.5 T.