Publications by authors named "Nobuyoshi Takashima"

Article Synopsis
  • A 44-year-old man experienced a range of neurological symptoms, including hand tremors, difficulty concentrating, abnormal vision, and lower limb stiffness, leading to falls.
  • Laboratory tests indicated significantly high serum creatine kinase levels and abnormal muscle discharges, prompting a diagnosis of Isaacs' syndrome based on a positive potassium channel antibody test.
  • While initial treatment with an anticonvulsant did not improve his condition, high-dose intravenous methylprednisolone therapy led to significant clinical improvement, suggesting its effectiveness compared to other treatments for Isaacs' syndrome.
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A 29-year-old female developed diplopia, nasal voice and gait disturbance after an upper respiratory infection. On admission, she presented with bilateral external ophthalmoplegia, slight bilateral facial nerve palsy, dysarthria, dysphagia, cervical and brachial muscle weakness, ataxia and areflexia. She had serum anti-GT1a, anti-GQ1b and anti-galactocerebroside IgG antibodies.

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Background/aims: The mechanisms underlying neurological deterioration in patients with acute lacunar infarction in the lenticulostriate artery (LSA) territory are currently unclear. We aimed to identify predictors for progressive neurological deficits using diffusion-weighted imaging (DWI).

Methods: We studied 40 consecutive patients who were classified into two groups based on their NIHSS scores: progressive infarction (PI) and non-progressive infarction (NPI).

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We report a 49-year-old man who was a human T-cell leukemia virus type 1 (HTLV-1) carrier, born in Okinawa prefecture where both strongyloidiasis and HTLV-1 are endemic. He presented with fever, headache and urinary retention. On the basis of CSF examination and MRI findings, his condition was diagnosed as myelitis.

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