Publications by authors named "Nobuyasu Wakazono"
Article Synopsis
- * This study included 127 severe asthma patients to assess ACO prevalence using specific criteria, comparing outcomes between those with and without ACO.
- * ACO was found in 31.5% of severe asthma patients, but it did not significantly impact the rates of exacerbations or the annual decline in lung function over the study period.
Article Synopsis
- The study examines how deteriorated sinusitis and increased fat-to-muscle ratio can affect the quality of life in asthma patients, regardless of any lung disease.
- Researchers used data from a specific asthma cohort to analyze the relationship between visceral fat to muscle ratios, sinus health scores, and quality of life as measured by the Asthma Quality of Life Questionnaire.
- Findings revealed that higher fat-to-muscle ratios and worse sinus scores were linked to lower quality of life scores in asthma patients, indicating that these factors negatively impact well-being, independent of lung pathology.
Article Synopsis
- This study investigates the impact of mucus plugs and airway structure on airflow limitations and outcomes in COPD patients using two different cohorts.
- Patients were categorized based on the number of lung segments with mucus plugs, and both groups were evaluated for health-related independence and mortality over several years.
- Results indicated that high mucus scores are linked to reduced airflow and increased mortality, while lower airway counts are related to a greater loss of independence, highlighting the distinct roles of mucus and airway structure in COPD.
Adverse events are potentially associated with an IgG response after BNT162b2 vaccination for severe acute respiratory syndrome coronavirus 2. In this study, we investigated the side effects of the BNT162b2 vaccine using a health questionnaire and examined its relationship with IgG antibody titers. Serum samples were collected from participants 3 months after the second vaccination, immediately before the third vaccination, and 1 and 3 months after the third vaccination.
View Article and Find Full Text PDFThe mechanism of high transfer coefficients of the lungs for carbon monoxide (Kco) in non-smokers with asthma is explained by the redistribution of blood flow to the area with preserved ventilation, to match the ventilation perfusion. To examine whether ventilation heterogeneity, assessed by pulmonary function tests, is associated with computed tomography (CT)-based vascular indices and Kco in patients with asthma. Participants were enrolled from the Hokkaido-based Investigative Cohort Analysis for Refractory Asthma (Hi-CARAT) study that included a prospective asthmatic cohort.
View Article and Find Full Text PDFA 65-year-old woman presented to a local hospital with a 4-day history of cough, fever, and dyspnea. She had started using a composter and had been exposed to the vapor for 18 days before her first visit. She was diagnosed with acute eosinophilic pneumonia (AEP) based on her symptoms, the presence of bilateral pulmonary opacities on computed tomography, and alveolar eosinophilia confirmed by bronchoalveolar lavage.
View Article and Find Full Text PDFA 60-year-old woman, a care worker with no known comorbidities, presented to the pulmonary clinic for assessment of a left hilar tumor detected on chest radiography. She had a history of oophorocystectomy and was a 0.5-pack/day smoker.
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