[Long-term study of nipradilol ophthalmic solution in patients with normal-tension glaucoma].

Purpose: We investigated the long-term clinical effects of a nipradilol ophthalmic solution on normal-tension glaucoma.

Methods: Among normal tension glaucoma patients who consulted the Nara Medical University Hospital or 2 affiliated hospitals between November 2001 and August 2002, we prospectively examined intraocular pressure-decreasing effects, the deterioration of visual field defects, and the appearance of side effects in 46 patients who underwent single therapy with a nipradilol ophthalmic solution. We evaluated intraocular pressure at 6-month intervals.

Objective visual field evaluation using multifocal visual evoked potentials in patients with intracranial disease complicated by mental disorders.

Objectives: We investigated whether visual field defects can be objectively evaluated using multifocal visual evoked potentials (mfVEPs) in patients with intracranial disease complicated by mental disorders.

Patients And Methods: First, to determine the normal pattern of mfVEPs, recordings were performed using a VERIS Junior Science recording apparatus (Mayo, Aichi, Japan) in 40 healthy subjects. Responses from 8 sites in each subject were divided into 4 quadrants (superior and inferior temporal quadrants and superior and inferior nasal quadrants).