Objectives: L-4-borono-2-F-fluoro-phenylalanine (L-[F]FBPA), a substrate of L-type amino acid transporter 1 (LAT1), is a tumor-specific probe used in positron emission tomography (PET). On the other hand, it has not been examined whether another isomer D-[F]FBPA accumulates specifically in the tumor. Here, we compared the accumulation of D-[F]FBPA in C6 glioma and inflammation to evaluate the performance of D-[F]FBPA as a tumor-specific probe.
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