Evaluation of Caries-Free Restorations Bonded with Various Adhesive Systems: Study.

Purpose: Secondary caries originate from a leakage pathway where oral acids can penetrate faster and demineralize the tooth substrate deeper which can be visualized by dye penetration. The ability to prevent secondary caries by contemporary adhesive systems was evaluated in this study. Dye penetration distance through leakage and into the tooth substrate adjacent to Class V restorations after artificial caries exposure was compared.

Prognosis test by visualization of demineralized dentin under restorations to prevent initial wall-lesions initiated by lactic acid.

Purpose: To visualize the complete protection of restored dentin in the acidic environment by the complete impregnation of resin into demineralized dentin.

Methods: Class V cavities prepared in extracted human molars composed of enamel, cementum and dentin surfaces were sealed using either 4-META/MMA-TBB resin with conditioning periods of 10, 30, 60 seconds with 10% citric acid and 3% ferric chloride mixed aqueous solution (10-3) or Single-Bond 2 adhesives prior to restoration with light-cured resin-composite. Specimens were either immersed in artificial saliva or 0.

A 10-Year Clinical Evaluation of Resin-Bonded Fixed Dental Prostheses on Non-Prepared Teeth.

This study evaluated the conditions of the non-invasive resin-bonded fixed dental prostheses (FDP) and patient satisfaction up to 10 years of clinical function. A total of 23 patients who required fixed prostheses in the areas of mandibular anterior and premolar, and maxillary anterior region received resin-bonded restorations between 1999-2003. In 13 patients with 14 edentulous areas were restored with an adhesive pontic (natural tooth, acrylic and porcelain).

Direct Tensile Strength and Characteristics of Dentin Restored with All-Ceramic, Resin-Composite, and Cast Metal Prostheses Cemented with Resin Adhesives.

A dentin-cement-prosthesis complex restored with either all-porcelain, cured resin-composite, or cast base metal alloy and cemented with either of the different resin cements was trimmed into a mini-dumbbell shape for tensile testing. The fractured surfaces and characterization of the dentin-cement interface of bonded specimens were investigated using a Scanning Electron Microscope. A significantly higher tensile strength of all-porcelain (12.

Dentin protection by a primer-less adhesive technique.

Purpose: To identify the remaining demineralized dentin (the permeable layer that allows leakage) when using primer-less wet bonding with a total etching period of 10 to 60 seconds compared with contemporary resin adhesives.

Methods: Extracted human molars were selected and Class V cavities were prepared on the axial surfaces at the CEJ, providing margins in enamel and dentin for leakage testing using a basic dye (n = 10). Seven groups of conditioned teeth [1-1 etched for 10, 30, and 60 seconds (primer-less wet), All-Bond 2 and Single-Bond 2 (wet), AQ-Bond (self-etched), Super-Bond C&B (dry)] were used as bonding systems for resin composite restoration.

Influence of dentin substrates to simplify wet-bonding: a leakage-free and reliable tensile strength interface for long-lasting restorations.

The wet-bonding procedure can be simplified by eliminating the primer. An aqueous mixture of 1% citric acid and 1% ferric chloride (1-1) was hypothesized as providing an easier dehydratable thinner substrate to which 4-META/MMA-TBB resin can adhere reliably. The 1-1 was applied for 10 s and rinsed off with water for 10 s.

Marginal integrity between a prefabricated composite block and enamel, DEJ, and dentin.

Purpose: To evaluate the stability of the interfacial layer and leakage patterns between enamel, DEJ, dentin and three adhesive systems as demonstrated by either a dye or a silver nitrate technique to understand the marginal integrity of restored tooth substrates.

Methods: Extracted human molars were cross-sectioned to prepare enamel, DEJ and dentin surfaces. Areas with the DEJ aligned in the middle were restored with prefabricated flat composite blocks using either Superbond C&B (SB), Panavia Fluorocement (PN) or Variolink II (VL) cements.

Stress response of adherent cells on a polymer blend surface composed of a segmented polyurethane and MPC copolymers.

To better understand the effect of 2-methacryloyloxyethyl phosphorylcholine (MPC) copolymer in improving the biocompatibility of segmented polyurethane (SPU), the expression of heat shock protein (HSP) mRNA in HeLa S3 cells adhered on SPU blended with MPC copolymers was measured. Conventionally, MPC copolymers (PMEH) were synthesized by changing the feed ratios of MPC and 2-ethylhexyl methacrylate. X-ray photoelectron spectroscopic analysis of the SPU/PMEH film indicated that the surface concentration of MPC units on the SPU/PMEH film increased with an increase in PMEH composition.

Effect of remaining demineralised dentine on dental microleakage accessed by a dye penetration: how to inhibit microleakage?

Objectives: To demonstrate that microleakage has taken place at the defect, which was analysed previously by a tensile test using dumbbell shaped specimens trimmed from bonded resin/dentine restorations, and to suggest how microleakage can be inhibited reliably in dental treatment.

Methods: A total of 60 Class V box cavities were prepared at the cemento-enamel junction on fresh bovine incisors and randomly divided into four groups of 15 specimens each. Exposure times of etching for 10:3 conditioner were set at 10, 30 or 60 s, and for 10% phosphoric acid (positive control) at 10 s.

Importance of mini-dumbbell specimen to access tensile strength of restored dentine: historical background and the future perspective in dentistry.

Objectives: The development of adhesive resins to dentine enables resin restorations to be more durable. Several bond strength measurement techniques for measuring adhesion have been proposed. A standardised method is needed which produced higher and more consistent bond strength values which allow bond stability and the bonding mechanism to be studied.

Improved wet bonding of methyl methacrylate-tri-n-butylborane resin to dentin etched with ten percent phosphoric acid in the presence of ferric ions.

The objective of this study was to determine the influence of dissolved dentinal substances in demineralized dentin on the hybridization of resin for bonding to dentin. It was hypothesized that these substances, including polyelectrolytes, significantly change the substrates, which could then be assessed by the addition of Na(+), Ca(2+), or Fe(3+) in 10% phosphoric acid. Bovine dentin specimens were etched for 10 s with a solution of 10% phosphoric acid (control) or of 22.

AFM observation of collapse and expansion of phosphoric acid-demineralized dentin.

The objective of this study is to provide additional data regarding morphological changes that occur to dentin matrices following demineralization with etchants. Our understanding of the mechanism of diffusion of comonomers into the demineralized substrate is very limited. It has been hypothesized that certain water-soluble polyelectrolytes (acidic proteins) and neutral proteins in dentin can influence the collapse of demineralized dentin when it is air dried.

In vitro and ex vivo blood compatibility study of 2-methacryloyloxyethyl phosphorylcholine (MPC) copolymer-coated hemodialysis hollow fibers.

To identify the advantages of 2-methacryloyloxyethyl phosphorylcholine (MPC) copolymer-coated polysulfone (PSf) hollow fibers for hemodialyzer and hemofilter minimodules with hollow fibers were made and blood compatibility was evaluated in vitro and ex vivo. Three types of hollow fibers, i.e.

Frictional properties of poly(MPC-co-BMA) phospholipid polymer for catheter applications.

A fundamental understanding of surface properties of the biomaterials at a nanometer scale should be generated in order to understand cellular responses of the tissue to biomaterials thereby minimizing or eliminating tissue trauma at a macrometer scale. In this study poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate) ([poly(MPC-co-BMA]) was evaluated as a potential coating material for vascular applications to provide smooth catheterization using atomic force microscopy (AFM) techniques.A uniform coating of [poly(MPC-co-BMA] equivalent to a thickness of 2.

Reduced adhesion of blood cells to biodegradable polymers by introducing phosphorylcholine moieties.

Aliphatic polyesters are believed to be good biocompatible polymers for tissue engineering because of their biodegradability and nontoxicity of the degradated products. However, it is necessary to reduce the nonspecific protein adsorption for the application of biodegradable polymers to drug delivery systems or antiadhesive membranes. We hypothesized that novel biodegradable polymers could be synthesized by introducing phosphorylcholine moieties into aliphatic polyesters.

Dental biomaterials and the healing of dental tissue.

This paper addresses the application of new adhesive technologies to dentistry. The bonding of synthetic polymers to dentin is difficult and it has taken a long time to produce reliable methods. Success has been achieved suing a 4-methacryloyloxyethyltrimellitate anhydride/methyl methacrylate-tri-n-butyl borane system which allows the generation of a layer of hybridised dentin.

Improving a self-curing dental resin by eliminating oxygen, hydroquinone and water from its curing process.

Self-curing dental resins are always manipulated in the presence of curing inhibitory factors such as oxygen, hydroquinone, water and another contaminants such as saliva and blood. The purpose of this study was to elucidate the effects of eliminating these curing inhibitory factors on resin properties. Several clinically relevant characteristics of an experimental resin cured in the absence of inhibitory factors (purified group) were determined and compared with the resin cured conventionally (control group).

Suppression of the inflammatory response from adherent cells on phospholipid polymers.

The expression of interleukin-1beta (IL-1beta) messenger RNA (mRNA) in macrophage-like cells cultured on phospholipid polymers was evaluated to determine the extent of the inflammatory response. As phospholipid polymers, poly(2-methacryloyloxyethyl phosphorylcholine(MPC)-co-n-butyl methacrylate(BMA)s (PMBs) were synthesized. Poly(ethylene terephthalate) (PET), poly(2-hydroxyethyl methacrylate) (PHEMA), and segmented poly(ether urethane) (Tecoflex 60) were used as reference biomedical polymers.

Comparison of microleakage of three acid-base luting cements versus one resin-bonded cement for Class V direct composite inlays.

Statement Of Problem: Demineralized dentin beneath set cement may adversely affect microleakage under fixed restorations.

Purpose: Microleakage of direct composite inlays cemented with acid-base cements and a methyl methacrylate resin cement were evaluated to determine their effect on the integrity of the underlying hybridized dentin.

Materials And Methods: Sixty Class V box preparations (3 mm x 3 mm x 1.

Physical properties and blood compatibility of surface-modified segmented polyurethane by semi-interpenetrating polymer networks with a phospholipid polymer.

Segmented polyurethanes, (SPU)s, are widely used in the biomedical fields because of their excellent mechanical property. However, when blood is in contact with the SPU, non-specific biofouling on the SPU occurs which reduces its mechanical property. To obtain novel blood compatible elastomers, the surface of the SPU was modified with 2-methacryloyloxyethyl phosphorylcholine (MPC) by forming a semi-interpenetrating polymer network (semi-IPN).

A nonthrombogenic gas-permeable membrane composed of a phospholipid polymer skin film adhered to a polyethylene porous membrane.

Polymer membranes are widely used in biomedical applications such as hemodialysis, membrane oxygenator, etc. When the membranes come in contact with blood or body fluids, protein adsorption and cell adhesion occur rapidly. Nonspecific protein adsorption and cell adhesion on the membranes induce not only various bio-rejections but also a decrease in their performance.

The vascular prosthesis without pseudointima prepared by antithrombogenic phospholipid polymer.

On the luminal surface of the common synthetic vascular prostheses, blood coagulation can occur and a thrombus membrane is formed when blood flow passes through it. The thrombus membrane should be organized according to the wound healing process and it becomes a pseudointima which could serve as a blood conduit. However, the small-diameter vascular prosthesis may be quickly occluded by the initial thrombus.