[A Case of Spontaneous Rupture of Non-Viral Hepatocellular Carcinoma with Subcapsular Hematoma].

An 86-year-old man visited our hospital complaining of upper abdominal pain. Enhanced computed tomography showed a 37×23mm tumor with subcapsular hematoma in S3. Hepatitis B and C virus markers were negative, and serum tumor markers were elevated.

Mammary and extramammary Paget's disease.

Paget's disease, described by Sir James Paget in 1874, is classified as mammary and extramammary. The mammary type is rare and often associated with intraductal cancer (93-100% of cases). It is more prevalent in postmenopausal women and it appears as an eczematoid, erythematous, moist or crusted lesion, with or without fine scaling, infiltration and inversion of the nipple.

[A case of adenocarcinoma of the anal canal in which palliation was achieved by chemoradiotherapy].

An 82-year-old man who complained of constipation, anal pain, and bleeding was diagnosed with internal hemorrhoid in another hospital 6 months previously. At the time of our consultation, a tumor was observed in the anal canal. Computed tomography (CT) imaging revealed that the tumor extended to the front of the coccyx with abscess formation.

[Experience with levocarnitine chloride supplementation for the treatment of fatigue in cancer patients undergoing chemotherapy].

Aim: Patients undergoing chemotherapy are at risk of carnitine deficiency, and carnitine supplementation has been demonstrated to improve cancer-related fatigue. We examined the changes in fatigue when cancer patients experiencing fatigue while undergoing chemotherapy were administered levocarnitine chloride.

Materials And Methods: Ten patients with advanced and recurrent cancer experiencing fatigue during chemotherapy were administered levocarnitine chloride.

[A case of gastric cancer with para-aortic lymph node metastasis successfully treated with S-1/paclitaxel/lentinan combination therapy].

A 70-year-old male presented with gastric cancer with para-aortic lymph node metastasis. The patient was given combination chemotherapy of S-1, paclitaxel and Lentinan. Lymph node metastases were reduced in number at the end of one course.

[A case of unresectable sigmoid colon cancer in an elderly patient responding to S-1].

An 88-year-old man with unresectable sigmoid colon cancer due to retroperitoneal invasion and massive LN metastasis was treated with S-1 after colostomy. S-1 (80 mg/body/day) was administered for 2 weeks followed by a one week interval. Colonoscopy and abdominal CT revealed a partial response.

Combined treatment with selective cyclooxygenase-2 inhibitor and fluorinated pyrimidines for liver metastasis of colon cancer.

Liver metastasis is a major contributor to mortality in patients with colorectal cancer. Hence, it is essential to establish preventive therapy to control liver metastasis. Recently, it has become widely accepted that cyclooxygenase (COX)-2 inhibitors possess anti-cancer activity for various types of tumor, especially colorectal.

Thoracoscopic excision for ectopic mediastinal parathyroid tumor.

Ectopic parathyroid adenoma or hyperplasia in the mediastinum are seen in a percentage of patients with hyperparathyroidism and have generally been treated by conventional open surgery. However, due to recent improvements in the ability of diagnostic imaging such as 99mTc-methoxyisobutylisonitrile (MIBI) scintigraphy to identify these lesions, we have been obtaining favorable results from thoracoscopic excision of mediastinal parathyroid tumors. In thoracoscopic surgery, three to four trocars were inserted between the fourth and seventh ribs from a lateral approach.