A Method to Locally Irradiate Specific Organ in Model Organisms Using a Focused Heavy-Ion Microbeam.

The functions of organisms are performed by various tissues composed of different cell types. Localized irradiation with heavy-ion microbeams, which inactivate only a portion of the constituent cells without destroying the physical intercellular connections of the tissue, is a practical approach for elucidating tissue functions. However, conventional collimated microbeams are limited in the shape of the area that can be irradiated.

Enhancement of beam pulse controllability for a single-pulse formation system of a cyclotron.

The single-pulse formation technique using a beam chopping system consisting of two types of high-voltage beam kickers was improved to enhance the quality and intensity of the single-pulse beam with a pulse interval over 1 μs at the Japan Atomic Energy Agency cyclotron facility. A contamination rate of neighboring beam bunches in the single-pulse beam was reduced to less than 0.1%.

Influence of injection beam emittance on beam transmission efficiency in a cyclotron.

The JAEA AVF cyclotron accelerates various kinds of high-energy ion beams for research in biotechnology and materials science. Beam intensities of an ion species of the order of 10(-9)-10(-6) ampere are often required for various experiments performed sequentially over a day. To provide ion beams with sufficient intensity and stability, an operator has to retune an ion source in a short time.

Useful technique for analysis and control of the acceleration beam phase in the azimuthally varying field cyclotron.

We have developed a new technique for analysis and control of the acceleration beam phase in the cyclotron. In this technique, the beam current pattern at a fixed radius r is measured by slightly scanning the acceleration frequency in the cyclotron. The acceleration beam phase is obtained by analyzing symmetry of the current pattern.

Single-turn extraction from a K110 AVF cyclotron by flat-top acceleration.

Single-turn extraction from the Japan Atomic Energy Agency AVF cyclotron with a K number of 110 using a flat-top (FT) acceleration system has been achieved to reduce the energy spread of an ion beam for microbeam formation with energy up to hundreds of MeV and to increase extraction efficiency from the cyclotron. In order to generate a FT waveform voltage using the fifth-harmonic frequency on a dee electrode, a FT resonator was designed using MAFIA code to achieve downsizing and low power consumption. The FT resonator, coupled to the main resonator through a coupling capacitor, covered the full range of the fifth harmonic frequency from 55 to 110 MHz.

Characteristics of focusing high-energy heavy ion microbeam system at the JAEA AVF cyclotron.

Ion optical analysis was made for a new focusing high-energy heavy ion microbeam system connected to the AVF cyclotron (K=110) at the accelerator facility, TIARA of JAEA Takasaki. The focusing performance of the microbeam system was estimated from both the calculation up to third-order term using TRANSPORT code and the measurement of beam resolution with the secondary electron imaging. As a result, a minimum beam size was evaluated at 0.