Objective: Mental defeat and cognitive flexibility have been studied as explanatory factors for depression and posttraumatic stress disorder. This study examined mental defeat and cognitive flexibility scores in patients with panic disorder (PD) before and after cognitive behavioral therapy (CBT), and compared them to those of a gender- and age-matched healthy control group.
Results: Patients with PD (n = 15) received 16 weekly individual CBT sessions, and the control group (n = 35) received no treatment.