Publications by authors named "Nobuhiro Komiya"

: The Wakayama prefecture is endemic for two types of tick-borne rickettsioses: Japanese spotted fever (JFS) and scrub typhus (ST). Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne hemorrhagic viral disease with a high mortality rate and is often difficult to differentiate from such rickettsioses. SFTS cases have recently increased in Wakayama prefecture.

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  • - This study examined the pretravel consultation (PTC) of older adults (60+) in Japan to understand their vaccination habits and health concerns when traveling abroad, using data from the Japan Pre-travel Consultation Registry (J-PRECOR).
  • - Out of 1000 clients studied, 523 received a yellow fever vaccine, but only 38.6% of those not vaccinated received the tetanus vaccine, and just 25.7% were prescribed malaria prophylaxis for short trips to high-risk areas.
  • - The results indicate a need for increased preventive measures for older travelers, showing that younger age and lower hepatitis A vaccination rates are linked to receiving yellow fever vaccination.
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  • Japanese spotted fever (JSF), a tick-borne illness caused by Rickettsia japonica, has seen rising cases, with a notable cluster of seven reported for the first time in Japan's literature, linked to a cemetery visit in late 2019.
  • This outbreak was linked to an increase in cemetery visitors during a Buddhist event and a surge in infectious tick larvae, highlighting the role of environmental factors in disease spread.
  • Effective management of the outbreak involved prompt collaborative response from clinical, laboratory, and public health sectors, emphasizing the need for early intervention to prevent severe disease outcomes.
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In retrospective analyses, we report 3 febrile patients in Japan who had seroconversion to antibodies against Ehrlichia chaffeensis antigens detected by using an immunofluorescence and Western blot. Our results provide evidence of autochthonous human ehrlichiosis cases and indicate ehrlichiosis should be considered a potential cause of febrile illness in Japan.

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Background: Coronavirus disease 2019- (COVID-19-) associated cytotoxic lesions of the corpus callosum (CLOCCs) have been reported as a rare neurological abnormality in severe cases. Here, a case of CLOCCs in the early stages of mild COVID-19 infection during the Omicron BA.1 epidemic is reported along with a literature review.

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Background: Awareness of pre-travel consultations (PTCs) and prevention methods for overseas travel-related diseases, and the understanding of PTCs among Japanese travelers and medical professionals remains low in Japan. A multicenter registry was established to examine PTCs in Japan. This study assessed the PTC implementation rate and examined the indicators of PTCs that can be used as criteria for evaluating quality.

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Purpose: Radiation protection glasses is a useful tool for dose reduction of eye lens. However, the method to evaluate the dose of eye lens, which is covered with radiation protection glasses in actual radiation management situation, has not been established. We invented the easy-to-use procedure to estimate the dose of eye lens inside of radiation protection glasses for occupationally exposed person using an X-ray shielding material and an additional personal dosimeter for trunk of the body.

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Introduction: In response to global outbreaks of infectious diseases, the need for support from organizations such as the World Health Organization Global Outbreak Alert and Response Network (GOARN) is increasing. Identifying the obstacles and support needs for applicants could increase GOARN deployments from Japan.

Methods: This cross-sectional study involved a web-based, self-administered questionnaire survey targeting Japanese participants in the GOARN Tier 1.

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We describe the clinical features of a 75-year-old man who presented to our hospital with frequent urination for 3 months. Retrograde urethrography showed extended and continuous narrowing of the stricture in the anterior urethra. Cystourethroscopy showed extended narrowing of the urethral lumen without normal membrane.

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Postpartum thyroiditis (PPT) is characterized by mild thyrotoxicosis occurring within one year of parturition commonly followed by transient hypothyroidism. Having genetic background of autoimmune thyroid disorders is a risk factor for it because the immune reactivation during postpartum period is a trigger for PPT. Pandemic of COVID-19: caused by SARS-CoV-2 infection is a global health problem, and occurrence of Graves' disease and Hashimoto's thyroiditis after the viral infection have been reported but occurrence of PPT with COVID-19 has never been reported.

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Article Synopsis
  • * Two of the patients remained positive for the virus three weeks after their symptoms began, and all displayed bilateral ground glass opacities on CT scans.
  • * The report emphasizes the challenges of diagnosing COVID-19 based on common symptoms like fever and cough, suggesting that PCR tests and CT scans are essential for accurate diagnosis.
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Purpose: To evaluate the diagnostic performance of chest CT to differentiate coronavirus disease 2019 (COVID-19) pneumonia in non-high-epidemic area in Japan.

Materials And Methods: This retrospective study included 21 patients clinically suspected COVID-19 pneumonia and underwent chest CT more than 3 days after the symptom onset: six patients confirmed COVID-19 pneumonia by real-time reverse-transcription polymerase chain reaction (RT-PCR) and 15 patients proved uninfected. Using a Likert scale and its receiver operating characteristic curve analysis, two radiologists (R1/R2) evaluated the diagnostic performance of the five CT criteria: (1) ground glass opacity (GGO)-predominant lesions, (2) GGO- and peripheral-predominant lesions, (3) bilateral GGO-predominant lesions; (4) bilateral GGO- and peripheral-predominant lesions, and (5) bilateral GGO- and peripheral-predominant lesions without nodules, airway abnormalities, pleural effusion, and mediastinal lymphadenopathy.

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Most radiation protection items made from modern lead contain 210Pb. This study estimated the impact on eye lens of radiation derived from the 210Pb in three types of radiation protection glasses. The counts from the glasses were measured using a Geiger-Müeller survey meter.

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is a major causative organism of swine erysipelas, but the infection has rarely occurred in humans. A soft-tissue infection with this organism is described as "erysipeloid." Most reported cases in human are related to occupational exposure.

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Toxocariasis causes a variety of symptoms. We experienced a case of toxocariasis which was initially treated with steroids for Eosinophilic Granulomatosis with Polyangitis (EGPA). A 53-year-old woman with the past medical history of bronchial asthma presented at the outpatient department in the middle of August.

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While ebola virus disease (EVD) outbreak in West Africa seemed to be subsided, there are still some sporadic cases reported from the field. Many studies were conducted during the outbreak. It was identified that the virus can survive for a long period in certain areas of the survivors and they can be a reservoir.

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The largest ever outbreak of Ebola virus disease has been spreading in West Africa. The authors were deployed to Liberia and Sierra Leone as short-term consultants for the World Health Organization. Our mission was to ensure clinical management and infection prevention and control priorities in frontline treatment centres.

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During an epidemiologic investigation of pandemic influenza (H1N1) 2009 virus infection in May 2009 in Osaka, Japan, we found 3 clusters in which virus transmission occurred during the presymptomatic phase. This finding has public health implications because it indicates that viral transmission in communities cannot be prevented solely by isolating symptomatic case-patients.

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After returning from Thailand, a 23-year-old Japanese man was admitted because of fever, sore throat, neck pain, and chest pain. Contrasted-enhanced CT scanning of his neck revealed an absence of flow through the right internal jugular vein representing thrombosis, and moreover, an increase in wall thickness of the right internal jugular vein and enhancement of the surrounding tissue representing thrombophlebitis. Lung abscesses were also identified by a chest CT scan.

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A 56-year-old previously healthy man was admitted to our hospital for disordered consciousness, anuria, and severe jaundice. The patient had not travelled recently, but he worked at a fish market in Tokyo. From his history and clinical observation we suspected Weil's disease and started the corresponding treatment.

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A 32-year-old Japanese woman admitted November 1 for a 4-day fever and who had traveled in India October 14-22 was found to have no abnormal findings except for fever and luekocytopenia and thrombocytopenia. Negative rapid-test anti-dengue virus IgM antibody findings, however, became positive on hospital 2, with hemophagocytic cells found in the bone marrow, yielding a definitive diagnosis of dengue fever with viral-associated hemophagocytic syndrome. Some such cases with hemophagocytic syndrome have been reported in patients with sever dengue fever, but the rarity of the need for bone marrow examination means that it is unknown whether hemophagocytic syndrome occurs in mild dengue fever or whether our case was unusual.

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