Single-Fraction Palliative High-Dose-Rate Brachytherapy for Symptom Management in a 97-Year-Old Patient With Dementia.

Delivering cancer treatment to elderly patients with dementia is often challenging. We describe performing palliative surface mold brachytherapy (SMBT) in an elderly patient with advanced dementia for pain control using music therapy to assist with agitation. The patient was a 97-year-old Japanese woman with advanced dementia.

Preferential induction of endothelin-1 in a human epidermal equivalent model by narrow-band ultraviolet B light sources.

Narrow-band ultraviolet B (NB-UVB; 310-315 nm) is commonly used to treat vitiligo, but the mechanisms underlying the therapeutic effect have not been understood completely. Here, we evaluated the effects of broadband UVB (BB-UVB), NB-UVB, 308 nm xenon chloride (XeCl) excimer laser, and 308 nm XeCl excimer light on the expression of endothelin-1 (ET-1) in a cultured human epidermal tissue model. Our results provide a theoretical basis for the effectiveness of UVB irradiation, including excimer light and excimer laser, in the treatment of vitiligo.

Evaluation of the clinical and immunohistological efficacy of the 585-nm pulsed dye laser in the treatment of psoriasis.

Background: The 585-nm pulsed dye laser (PDL) therapy is useful for the patients with psoriasis. PDL treatment is based on selective photothermolysis of the dermal vasculature.

Objective: The objectives of this study were to evaluate the clinical and immunohistological effects of PDL on psoriasis and to examine the association between psoriatic dermal vasculature and the clinical effects.

Clinical effect of low-energy double-pass 1450 nm laser treatment for acne in Asians.

Background: While the 1450 nm diode laser is highly effective for the treatment of acne, its use is associated with considerable pain. Low-energy, double-pass irradiation was attempted as an alternative to prevent the occurrence of pain as an adverse effect.

Purpose: This study aimed to evaluate the clinical efficacy of low-energy, double-pass, 1450 nm diode laser treatment in the treatment of acne in Asian patients.

A new targeted blue light phototherapy for the treatment of acne.

Background: The effects of blue light phototherapy on inflammatory acne lesions were recently investigated. Many reports have used high-intensity, narrow-band 420 nm UV-free blue light delivery systems. The aim of this study was to evaluate a new blue light system (MultiClear) for targeted blue light phototherapy.

Comparison of the efficacy of calcipotriol and maxacalcitol in combination with narrow-band ultraviolet B therapy for the treatment of psoriasis vulgaris.

Background: Combination treatment with topical vitamin D(3) and narrow-band ultraviolet B (UVB) radiation is effective against psoriasis vulgaris. We compared the efficacy of the topical vitamin D(3) derivatives calcipotriol and maxacalcitol in combination therapy.

Materials And Methods: In this retrospective observational study, 21 patients admitted to Nagoya City University Hospital between April 2001 and September 2004 were enrolled.

Bednar tumor: a report of two cases.

We have recently treated two Japanese with Bednar tumor, pigmented dermatofibrosarcoma protuberans. The tumors were multilobular with brown-pigmentation and an irregular surface. Firm nodules were growing into the deep subcutaneous tissue, but they were movable over the underlying tissue.