Increased prevalence of metabolic syndrome in female patients with overactive bladder: A population-based study.

Objectives: To assess the association between overactive bladder syndrome (OAB) and the metabolic syndrome (MetS).

Patients And Methods: A population-based study was conducted to compare OAB patients with age-, sex- and ethnicity-matched control subjects regarding the prevalence of the parameters of the MetS, with respect to obesity, hyperlipidemia, hypertension and diabetes mellitus. The characteristics of the OAB population were assessed.

Summary Paper of the Updated 2023 European Association of Urology Guidelines on Urological Trauma.

Context: The European Association of Urology (EAU) Guidelines Panel for Urological Trauma has produced guidelines in order to assist medical professionals in the management of urological trauma in adults for the past 20 yr. It must be emphasised that clinical guidelines present the best evidence available to the experts, but following guideline recommendations will not necessarily result in the best outcome. Guidelines can never replace clinical expertise when making treatment decisions for individual patients regarding other parameters such as experience and available facilities.

[THE USE OF BOTULINUM TOXIN IN UROLOGY].

Botulinum toxin is an accepted therapy for several urologic diseases involving the lower urinary tract system. Intravesical injection of the toxin emerged in recent decades as an evidenced-based approach for the treatment of patients with medication refractory neurogenic or idiopathic detrusor over-activity. The use of the toxin for other urologic disease such as benign prostate enlargement, detrusor-sphincter dyssynergia or premature ejaculation - still requires further research.

[TEST FOR NEUTRALIZING ANTIBODIES IN UROLOGIC PATIENTS WITH NO RESPONSE TO INTRAVESICAL BOTULINUM TOXIN INJECTIONS].

Botulinum toxin has been at the center of attention in the last decades as a treatment option in several urologic diseases related to lower urinary tract function. Intravesical injection of the toxin is recommended for two main indications: neurogenic detrusor over-activity and idiopathic detrusor over-activity, resistant to oral therapy. In certain cases, clinical response to treatment is less than ideal, despite previous response.

European Association of Urology Guidelines Office Rapid Reaction Group: An Organisation-wide Collaborative Effort to Adapt the European Association of Urology Guidelines Recommendations to the Coronavirus Disease 2019 Era.

The coronavirus disease 2019 (COVID-19) pandemic is unlike anything seen before by modern science-based medicine. Health systems across the world are struggling to manage it. Added to this struggle are the effects of social confinement and isolation.

Renal trauma: the current best practice.

The kidneys are the most vulnerable genitourinary organ in trauma, as they are involved in up to 3.25% of trauma patients. The most common mechanism for renal injury is blunt trauma (predominantly by motor vehicle accidents and falls), while penetrating trauma (mainly caused by firearms and stab wound) comprise the rest.

Secondary enuresis and urological manifestations in children with ataxia telangiectasia.

Background: Ataxia telangiectasia (AT) is a neurodegenerative cerebellar disorder, caused by mutations in the ATM gene, involved in DNA repair. Radiosensitivity, progressive ataxia, immune deficiency and malignancies, are well known symptoms, but urological manifestations are scarcely described.

Objective: To characterize urologic manifestations in a large cohort of AT patients.

Low Intensity Shock Wave Treatment for Erectile Dysfunction-How Long Does the Effect Last?

Purpose: We studied the long-term efficacy of penile low intensity shock wave treatment 2 years after an initially successful outcome.

Materials And Methods: Men with a successful outcome of low intensity shock wave treatment according to the minimal clinically important difference on the IIEF-EF (International Index of Erectile Function-Erectile Function) questionnaire were followed at 6, 12, 18 and 24 months. Efficacy was assessed by the IIEF-EF.

Clinical Problem Solving: A Tobacco Merchant Who Can't Spit.

A 47 year old man presented with a combination of dry mouth and lightheadedness while standing. His medical background was unremarkable except for cigarette smoking and hyperlipidemia. Sjögren's syndrome was ruled out, and he was referred for evaluation of orthostatic hypotension, which by then included syncopal episodes and injuries.

Outcomes of Early Endoscopic Realignment Versus Suprapubic Cystostomy and Delayed Urethroplasty for Pelvic Fracture-related Posterior Urethral Injuries: A Systematic Review.

Context: The evidence base for optimal acute management of pelvic fracture-related posterior urethral injuries needs to be reviewed because of evolving endoscopic techniques. The current standard of care is suprapubic cystostomy followed by delayed urethroplasty.

Objective: To systematically review the evidence base comparing early endoscopic realignment with cystostomy and delayed urethroplasty regarding stricture rate, the need for subsequent procedures, and functional outcomes.

Penile Low Intensity Shock Wave Treatment is Able to Shift PDE5i Nonresponders to Responders: A Double-Blind, Sham Controlled Study.

Purpose: We performed sham controlled evaluation of penile low intensity shock wave treatment effect in patients unable to achieve sexual intercourse using PDE5i (phosphodiesterase type 5 inhibitor).

Materials And Methods: This prospective, randomized, double-blind, sham controlled study was done in patients with vasculogenic erectile dysfunction who stopped using PDE5i due to no efficacy. All patients had an erection hardness score of 2 or less with PDE5i.

Review of the current management of upper urinary tract injuries by the EAU Trauma Guidelines Panel.

Context: The most recent European Association of Urology (EAU) guidelines on urological trauma were published in 2014.

Objective: To present a summary of the 2014 version of the EAU guidelines on upper urinary tract injuries with the emphasis upon diagnosis and treatment.

Evidence Acquisition: The EAU trauma guidelines panel reviewed literature by a Medline search on upper urinary tract injuries; publication dates up to December 2013 were accepted.

Review of the current management of lower urinary tract injuries by the EAU Trauma Guidelines Panel.

Context: The most recent European Association of Urology (EAU) guidelines on urologic trauma were published in 2014.

Objective: To present a summary of the 2014 version of the EAU guidelines on urologic trauma of the lower urinary tract with an emphasis on diagnosis and treatment.

Evidence Acquisition: The EAU Trauma Panel reviewed the English-language literature via a Medline search for lower urinary tract injury (LUTI) up to November 2013.

The impact of vaginal penetration difficulties on the sexual functioning of women and their male partners.

Objectives: To compare the sexual function of women with and without vaginal penetration difficulties (VPDs) and relate it to the sexual function of their male partners.

Methods: All consenting women attending a sexual medicine centre during 2005-2007 completed the Female Sexual Function Index (FSFI) and answered questions about five VPDs (placement of a tampon, gynaecological examination, insertion of her or her partner's finger, and penile-vaginal intercourse). Male partners filled the International Index of Erectile Function (IIEF).

Penile low-intensity shock wave therapy: a promising novel modality for erectile dysfunction.

Penile extracorporeal low-intensity shock wave therapy (LIST) to the penis has recently emerged as a novel and promising modality in the treatment of erectile dysfunction (ED). LIST has angiogenic properties and stimulates neovascularization. If applied to the corpora cavernosa, LIST can improve penile blood flow and endothelial function.

Low-Intensity Extracorporeal Shock Wave Therapy in Vascular Disease and Erectile Dysfunction: Theory and Outcomes.

Introduction: Low-intensity extracorporeal shock wave therapy (LI-ESWT) to the penis has recently emerged as a new and promising modality in the treatment of erectile dysfunction (ED).

Aim: To review the published literature on the mechanism of action of LI-ESWT; and to report our clinical data on its efficacy in men with vasculogenic ED.

Methods: A Medline search using the relevant keywords on this topic has been done.

Shockwave treatment of erectile dysfunction.

Low-intensity extracorporeal shock wave therapy (LI-ESWT) is a novel modality that has recently been developed for treating erectile dysfunction (ED). Unlike other current treatment options for ED, all of which are palliative in nature, LI-ESWT is unique in that it aims to restore the erectile mechanism in order to enable natural or spontaneous erections. Results from basic science experiments have provided evidence that LI-ESWT induces cellular microtrauma, which in turn stimulates the release of angiogenic factors and the subsequent neovascularization of the treated tissue.

EAU guidelines on iatrogenic trauma.

Context: The European Association of Urology (EAU) Trauma Guidelines Panel presents an updated iatrogenic trauma section of their guidelines. Iatrogenic injuries are known complications of surgery to the urinary tract. Timely and adequate intervention is key to their management.

Long-term urinary bladder function following unilateral refluxing low loop cutaneous ureterostomy.

Purpose: Unilateral low loop cutaneous ureterostomy (LLCU) has been offered as the preferred method of temporary urinary diversion in cases of massively dilated and refluxing ureters. We sought to explore whether LLCU is effective in preserving urinary bladder function in the long term.

Materials And Methods: The charts of all patients who had undergone temporary unilateral LLCU as newborns in the presence of massive vesico-ureteric reflux were retrospectively reviewed.

Renal angiomyolipoma: long-term results following selective arterial embolization.

Background: The treatment for and long-term outcome of renal angiomyolipoma (AML) at high-risk for bleeding has not been determined.

Objective: To evaluate the complication rates and the long-term outcomes among patients treated by selective arterial embolization (SAE) for a large or symptomatic renal AML.

Design, Setting, And Participants: Forty-one patients with 48 kidneys containing AML were treated by SAE at a single tertiary academic center.