Publications by authors named "Noah J Timko"

Article Synopsis
  • - The study aimed to compare the recovery speed and quality from rocuronium neuromuscular blockade (NMB) using two reversal agents, sugammadex and neostigmine, in geriatric patients undergoing spine surgery.
  • - Results showed that sugammadex led to a significantly faster recovery time (average 4 minutes) compared to neostigmine (average 26 minutes), with sugammadex demonstrating less variability in recovery time.
  • - Although sugammadex improved operating room efficiency and had less hemodynamic instability, both reversal agents did not differ in post-anesthesia care unit stay, first ambulation time, or total hospital duration.
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Ovarian cancer is the leading cause of cancer‑ associated mortality in the female reproductive system. Interleukin (IL)‑33 and its receptor IL 1 receptor like 1 (also termed ST2) are expressed by many cell types including epithelial cells. The role of IL‑33 in the pathogenesis of neoplasia remains controversial.

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Interleukin-33 (IL-33), a damage-associated molecular pattern molecule, is a cytokine within the IL-1 interleukin family that binds to the plasma membrane receptor suppression of tumorigenicity 2 on numerous cell types. IL-33 has been extensively studied in its role in autoimmune diseases, host responses to pathogens and allergens, and has been associated with tumorigenic effects in cancer research. The present study was performed to investigate the effects of IL-33 on colon cancer cells, based off the previous data that have demonstrated an anti-tumor effect of IL-33 on pancreatic cancer cells.

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