Publications by authors named "Noah J Connally"
Article Synopsis
- The genetic basis of traits is mainly polygenic and influenced by non-coding alleles, which are thought to have minor regulatory roles in gene expression.
- Despite having access to extensive gene expression and epigenomic data, few connections between genetic variants and gene activity have been established.
- A study identified 220 gene-trait pairs influenced by protein-coding variants, revealing little evidence that typical gene expression explains associations with complex traits, indicating a need for improved models to understand these complexities.
