Publications by Nizar El Kadiri

Publications by authors named "Nizar El Kadiri"

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Relation between plasma homocysteine, gene polymorphisms of homocysteine metabolism-related enzymes, and angiographically proven coronary artery disease.

Abdelilah Laraqui Abdellatif Allami Alain Carrié Alain Raisonnier Anne-Sofie Coiffard Nizar El Kadiri

Eur J Intern Med

October 2007

Article Synopsis

Hyperhomocyteinemia (HHcy) is linked to increased risk of coronary artery disease (CAD), and specific genetic mutations in MTHFR, MTR, and MTRR impact homocysteine levels.
CAD patients displayed significantly higher total homocysteine levels compared to controls, with smokers also showing elevated levels and a greater risk for CAD.
The MTHFR 1298C allele was more common in CAD patients and associated with risk for HHcy, while no significant differences were found for other mutations in MTR and MTRR.

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Thermolabile methylenetetrahydrofolate reductase C677T polymorphism and homocysteine are risk factors for coronary artery disease in Moroccan population.

Nawal Bennouar Abdellatif Allami Houssine Azeddoug Abdenbi Bendris Abdelilah Laraqui Nizar El Kadiri

J Biomed Biotechnol

June 2010

Increased plasma total homocysteine (tHcy) levels have been shown to be a risk factor for coronary artery disease (CAD). The common methylenetetrahydrofolate reductase C677T (MTHFR C677T) polymorphism has been reported to be a strong predictor of mild hyperhomocysteinaemia (HHcy). We assessed whether this mutation was associated with increased risk of CAD and plasma levels of tHcy.

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