Evaluation of muco-adhesive tacrolimus patch on caspase-3 induced apoptosis in oral lichen planus: a randomized clinical trial.

Background: The study compared the clinical effectiveness of topical Tacrolimus (TAC) in patches or gel with Triamcinolone acetonide (TRI) gel for erosive/atrophic oral lichen planus (OLP) and investigated the influence of these therapies on Caspase-3 expression as a marker of apoptosis.

Methods: Thirty patients were randomly assigned into three equal groups to receive either topical TAC 0.1% patch twice daily, topical TAC 0.

Validity and reliability of three-dimensional palatal superimposition of digital dental models.

Objective: To evaluate the validity and reliability of three-dimensional (3D) landmark-based palatal superimposition of digital dental models using Ortho Mechanics Sequential Analyzer (OMSA).

Methods: The sample consisted of pre- and post-treatment digital maxillary dental models of 20 orthodontic cases. For each case, the pre- and post-treatment digital models were superimposed using surface-based methods utilizing 3dMD Vultus and Invivo 5 software as well as a landmark-based method utilizing OMSA.

Reliability of linear and angular dental measurements with the OrthoMechanics Sequential Analyzer.

Introduction: The aim of this study was to evaluate the reliability of newly developed software in the assessment of orthodontic tooth movement 3 dimensionally.

Methods: The sample consisted of pretreatment and posttreatment computed tomography scans and plaster dental models of 20 orthodontic patients treated with a hyrax palatal expander as a part of their comprehensive orthodontic treatment. Dental-arch measurements, including arch widths, tooth inclinations, and angulation parameters, were measured on the scans using InvivoDental 3D imaging software (version 5.

Periodontitis and cardiovascular disease: Floss and reduce a potential risk factor for CVD.

There is evidence supporting an association between cardiovascular disease (CVD) and periodontitis. We determined whether patients with chronic periodontitis, who are otherwise healthy individuals, have higher serum concentrations of emerging risk markers of CVD such as C-reactive protein (CRP) and interleukin 6 (IL-6) and investigated the effect of subsequent periodontal treatment on the levels of these markers. A total of 40 individuals were included in the study.