Publications by authors named "Nivedita Verma"
Heat shock proteins in chronic pain: From molecular chaperones to pain modulators.
Neuropharmacology
December 2024
Article Synopsis
- * Heat shock proteins (HSPs) are essential in responding to stress and inflammation, affecting pain signaling and contributing to central sensitization in the spinal cord.
- * Research indicates that targeting HSPs could lead to new treatment options for chronic pain, with ongoing studies using AI and machine learning to enhance drug discovery related to HSPs.
Chemotherapy-induced neuropathic pain (CINP) is one of the most prominent and incapacitating complication associated with chemotherapeutic regimens. The exact mechanisms underlying CINP are not fully understood yet, which hampers the development of effective therapeutics. The current study has been designed to investigate the effect of bergenin on CINP and dissect the underlying cellular and molecular mechanisms.
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