Publications by authors named "Nivedhitha Mahendran"

Alzheimer's disease (AD) is the most uncertain form of Dementia in terms of finding out the mechanism. AD does not have a vital genetic factor to relate to. There were no reliable techniques and methods to identify the genetic risk factors associated with AD in the past.

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Alzheimer's is a progressive, irreversible, neurodegenerative brain disease. Even with prominent symptoms, it takes years to notice, decode, and reveal Alzheimer's. However, advancements in technologies, such as imaging techniques, help in early diagnosis.

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Ageing is associated with various ailments including Alzheimer 's disease (AD), which is a progressive form of dementia. AD symptoms develop over a period of years and, unfortunately, there is no cure. Existing AD treatments can only slow down the progression of symptoms and thus it is critical to diagnose the disease at an early stage.

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Major depressive disorder (MDD) is the most common mental disorder in the present day as all individuals' lives, irrespective of being employed or unemployed, is going through the depression phase at least once in their lifetime. In simple terms, it is a mood disturbance that can persist for an individual for more than a few weeks to months. In MDD, in most cases, the individuals do not consult a professional, and even if being consulted, the results are not significant as the individuals find it challenging to identify whether they are depressed or not.

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Gene Expression is the process of determining the physical characteristics of living beings by generating the necessary proteins. Gene Expression takes place in two steps, translation and transcription. It is the flow of information from DNA to RNA with enzymes' help, and the end product is proteins and other biochemical molecules.

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The present methods of diagnosing depression are entirely dependent on self-report ratings or clinical interviews. Those traditional methods are subjective, where the individual may or may not be answering genuinely to questions. In this paper, the data has been collected using self-report ratings and also using electronic smartwatches.

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