Predictors of Perceived Positive and Negative Consequences of Sexual Compliance.

Sexual compliance (i.e., consenting to sex without initial sexual desire) can have both positive and negative consequences for well-being.

Quantum anomalous Hall effect in a nonmagnetic bismuth monolayer with a high Chern number.

The quantum anomalous Hall effect (QAHE) with a high Chern number hosts multiple dissipationless chiral edge channels, which is of fundamental interest and promising for applications in spintronics. However, QAHE is currently limited in two-dimensional (2D) ferromagnets with Chern number . Using a tight-binding model, we put forward that Floquet engineering offers a strategy to achieve QAHE in 2D nonmagnets, and, in contrast to generally reported QAHE in 2D ferromagnets, a high-Chern-number is obtained accompanied by the emergence of two chiral edge states.

The BeP monolayer exhibits ultra-high and highly anisotropic carrier mobility and 29.3% photovoltaic efficiency.

Two-dimensional materials with a combination of a moderate bandgap, highly anisotropic carrier mobility, and a planar structure are highly desirable for nanoelectronic devices. This study predicts a planar BeP monolayer with hexagonal symmetry that meets the aforementioned desirable criteria using the CALYPSO method and first-principles calculations. Calculations of electronic properties demonstrate that the hexagonal BeP monolayer is an intrinsic semiconductor with a direct band gap of approximately 0.

Minimally invasive prone lateral retropleural or retroperitoneal antepsoas approach spinal surgery using the rotatable radiolucent Jackson table.

Background: Prone lateral spinal surgery for simultaneous lateral and posterior approaches has recently been proposed to facilitate surgical room efficiency. The purpose of this study is to evaluate the feasibility and outcomes of minimally invasive prone lateral spinal surgery using a rotatable radiolucent Jackson table.

Methods: From July 2021 to June 2023, a consecutive series of patients who received minimally invasive prone lateral spinal surgery for various etiologies by the same surgical team were reviewed.

Predictive equation derived from 6,497 doubly labelled water measurements enables the detection of erroneous self-reported energy intake.

Nutritional epidemiology aims to link dietary exposures to chronic disease, but the instruments for evaluating dietary intake are inaccurate. One way to identify unreliable data and the sources of errors is to compare estimated intakes with the total energy expenditure (TEE). In this study, we used the International Atomic Energy Agency Doubly Labeled Water Database to derive a predictive equation for TEE using 6,497 measures of TEE in individuals aged 4 to 96 years.

The MRI-based vertebral bone quality score is a predictor of pedicle screw loosening following instrumented posterior lumbar fusion.

Objective: To investigate the predictive ability of the MRI-based vertebral bone quality (VBQ) score for pedicle screw loosening following instrumented transforaminal lumbar interbody fusion (TLIF).

Methods: Data from patients who have received one or two-level instrumented TLIF from February 2014 to March 2015 were retrospectively collected. Pedicle screw loosening was diagnosed when the radiolucent zone around the screw exceeded 1 mm in plain radiographs.

TiO Nanosphere/MoSe Nanosheet-Based Heterojunction Gas Sensor for High-Sensitivity Sulfur Dioxide Detection.

With the growing severity of air pollution, monitoring harmful gases that pose risks to both human health and the ecological environment has become a focal point of research. Titanium dioxide (TiO) demonstrates significant potential for application in SO gas detection. However, the performance of pure TiO is limited.

Comprehensive multi-omics analysis identifies NUSAP1 as a potential prognostic and immunotherapeutic marker for lung adenocarcinoma.

While NUSAP1's association with various tumors is established, its predictive value for prognosis and immunotherapy in lung adenocarcinoma (LUAD) remains unconfirmed. We analyzed Nucleolar Spindle-Associated Protein 1 (NUSAP1) gene expression in TCGA and GTEx datasets and validated it in clinicopathological tissues using qRT-PCR and immunohistochemistry. Additionally, we investigated NUSAP1's relationship with patient prognosis across TCGA and five GEO cohorts.

Research on the application of functional near-infrared spectroscopy in differentiating subjective cognitive decline and mild cognitive impairment.

Introduction: Alzheimer's disease (AD) is a common neurological disorder. Based on clinical characteristics, it can be categorized into normal cognition (NC), subjective cognitive decline (SCD), mild cognitive impairment (MCI), and dementia (AD). Once the condition begins to progress, the process is usually irreversible.

PTN secreted by cardiac fibroblasts promotes myocardial fibrosis and inflammation of pressure overload-induced hypertrophic cardiomyopathy through the PTN-SDC4 pathway.

Aims: Hypertrophic cardiomyopathy (HCM) is characterized by unexplained left ventricular hypertrophy (LVH) with key pathologic processes including myocardial necrosis, fibrosis, inflammation, and hypertrophy, which are involved in heart failure (HF), stroke, and even sudden death. Our aim was to explore the communication network among various cells in the heart of transverse aortic constriction (TAC) surgery induced HCM mice.

Materials And Methods: Single-cell RNA-seq data of GSE137167 was downloaded from the Gene Expression Omnibus (GEO) database.

Hyperoxia-activated Nrf2 regulates ferroptosis in intestinal epithelial cells and intervenes in inflammatory reaction through COX-2/PGE2/EP2 pathway.

The lack of knowledge about the mechanism of hyperoxia-induced intestinal injury has attracted considerable attention, due to the potential for this condition to cause neonatal complications. This study aimed to explore the relationship between hyperoxia-induced oxidative damage and ferroptosis in intestinal tissue and investigate the mechanism by which hyperoxia regulates inflammation through ferroptosis. The study systematically evaluated the effects of hyperoxia on oxidative stress, mitochondrial damage, ferroptosis, and inflammation of intestinal epithelial cells both in vitro and in vivo.

Risk Factors and Incidence for In-Stent Restenosis with Drug-Eluting Stent: A Systematic Review and Meta-Analysis.

Background: Despite significant reductions in in-stent restenosis (ISR) incidence with the adoption of drug-eluting stents (DES) over bare metal stents (BMS), ISR remains an unresolved issue in the DES era. The risk factors associated with DES-ISR have not been thoroughly analyzed. This meta-analysis aims to identify the key factors and quantify their impact on DES-ISR.

Haplotype-Resolved Genotyping and Association Analysis of 1,020 β-Thalassemia Patients by Targeted Long-Read Sequencing.

Despite the well-documented mutation spectra of β-thalassemia, the genetic variants and haplotypes of globin gene clusters modulating its clinical heterogeneity remain incompletely illustrated. Here, a targeted long-read sequencing (T-LRS) is demonstrated to capture 20 genes/loci in 1,020 β-thalassemia patients. This panel permits not only identification of thalassemia mutations at 100% of sensitivity and specificity, but also detection of rare structural variants (SVs) and single nucleotide variants (SNVs) in modifier genes/loci.

Terahertz Radiation Driven Nonlinear Transport Phenomena in Two-Dimensional Tellurene.

Nonlinear electron transport induced by polarized terahertz radiation is studied in two-dimensional tellurene at room temperature. A direct current, quadratic in the radiation's electric field, is observed. Contributions sensitive to radiation helicity and polarization orientation as well as polarization independent current are found.

Natural variation in an HD-ZIP factor identifies its role in controlling apple leaf cuticular wax deposition.

Natural variation is an invaluable genetic resource for plant trait improvement. Here, we performed a genome-wide association study (GWAS) analysis and identified MdHDG5, which controls apple leaf cuticular wax. An A-to-G single-nucleotide polymorphism (SNP) on the HDG5 promoter is associated with HDG5 expression and hexacosanol content (a component of leaf cuticular wax).

Screening and molecular mechanism research on bile microRNAs associated with chemotherapy efficacy in perihilar cholangiocarcinoma.

The efficacy of hepatic arterial infusion chemotherapy (HAIC) with oxaliplatin (OXA) and 5-fluorouracil (5-Fu) for treating advanced perihilar cholangiocarcinoma (pCCA) has been demonstrated, yet the survival benefits of HAIC for pCCA patients vary. Here, we aimed to screen out HAIC resistance-related bile microRNAs (miRNAs) and explore the functions of specific bile miRNAs in pCCA based on high-throughput sequencing. Levels of bile miR-532-3p, miR-1250-5p, and miR-4772-5p were related to the survival of advanced pCCA patients after HAIC.

Fertility intention of young people of childbearing age in China after the implementation of the two-child policy-A systematic review and meta-analysis.

Background: In recent years, due to the continuous increase of China's aging population and the decline of birth rate, China 's population base has declined sharply, and the fertility problem of young people has attracted much attention from scholars. Therefore, this study aims to comprehensively analyze the fertility intentions of young people of childbearing age and their influencing factors, explore the reasons for China's low fertility rate, and provide a reasonable theoretical basis for the formulation of subsequent fertility-related policies.

Methods: A systematic literature search was conducted from January 2012 to September 2023 through the databases PubMed, Web of Science, Embase, CNKI, Wanfang, and VIP using keywords including fertility desire, fertility intention, fertility plan, fertility purpose, fertility motivation, youth, urban youth, school-age youth, childbearing age youth in Chinese; and fertility desire, fertility intention, fertility plan, fertility willingness, youth, young people, child-bearing youth, and school-age youth in English.

Proteomic and metabolomic exploration in relapse acute myeloid leukemia bone marrow supernatant combined with genetic characteristics.

Object: Aim to investigate the multi-omic characteristics of the bone marrow supernatant of relapsed acute myeloid leukemia (AML) and search for proteins and metabolites associated with relapse.

Methods: A total of 40 bone marrow supernatant from 7 patients with relapsed AML and 33 patients with non-relapsed AML were collected for proteomics and metabonomics analysis. Unsupervised clustering was used to discover the characteristics of proteins and metabolites.

Assessment of anti-MRSA activity of auranofin and florfenicol combination: a PK/PD analysis.

Aims: Methicillin-resistant Staphylococcus aureus (MRSA) is an important zoonotic pathogen with multidrug-resistant phenotypes increasingly prevalent in both human and veterinary clinics. This study evaluated the potential of auranofin (AF) as an antibiotic adjuvant to enhance the anti-MRSA activity of florfenicol (FFC) and established a pharmacokinetic/pharmacodynamic (PK/PD) model to compare the efficacy of FFC alone or in combination with AF against MRSA.

Methods And Results: We observed an increased susceptibility and significant synergistic effects of MRSA to FFC in the presence of AF.

The Protective Effects of Microbe Derived Antioxidants on Digestive Tissue Morphology, Functions, and Intestinal Microbiota Diversity of Exposed to Glyphosate.

The use of glyphosate (Gly) has caused unnecessary economic losses to the aquaculture industry, but research on the effect of Gly on is very limited. The aim of this study is to reduce the negative effects of Gly, reduce yield loss, and improve economic benefits through nutritional feed control technology. The experiment involved 80 crabs randomly divided into four groups: control group, Gly group (48.

In-Situ Grafting Strategy Enables Functional Separator for Advanced Lithium-Sulfur Batteries.

A functional separator is developed by in-situ grafting nickel tetraaminophthalocyanine (NiTAPc) onto the surface of polypropylene (PP). It is applied to inhibit the shuttle effect of polysulfides (PSs) in lithium-sulfur(Li-S) batteries. The characterization results showed that NiTAPc is highly dispersed and uniformly grafted onto PP separator.

NIR-responsive injectable nanocomposite hydrogels with enhanced angiogenesis for promoting full-thickness wound healing.

Angiogenesis plays a vital role in the treatment of full-thickness wounds. Deferoxamine (DFO) has been employed to promote neovascularization, however, smart drug delivery systems are needed to optimize its utilization. In this study, an injectable extracellular matrix (ECM)-mimicking hydrogel (HOG@P&D) was developed by leveraging the dynamic Schiff base and hydrogen bonds among a chitosan derivative (HACC), oxidized alginate (OSA), gelatin, and DFO-loaded polydopamine nanoparticles (P&D) for efficient wound healing.

Advanced imidazole-functionalized metal-organic framework-based dual-mode sensor for rapid detection of FLU pesticide residues in food.

In this study, an advanced imidazole-functionalized 2D metal-organic framework (HBU-169), {[Cd(L)HO](HO)}·(4HO)·(DMF) was presented, which possesses both fluorescent properties and oxidase-like activity. HBU-169 demonstrates the ability to detect fluazinam (FLU) via fluorescent and colorimetric modes. In the fluorescent mode, a pronounced fluorescence quenching is observed, with the limit of detection (LOD) of 1.

A self-learning magnetic Hopfield neural network with intrinsic gradient descent adaption.

Physical neural networks (PNN) using physical materials and devices to mimic synapses and neurons offer an energy-efficient way to implement artificial neural networks. Yet, training PNN is difficult and heavily relies on external computing resources. An emerging concept to solve this issue is called physical self-learning that uses intrinsic physical parameters as trainable weights.

Activation of the HIF1α/TIMP1/MT6-MMP pathway is associated with invasion in pituitary null cell adenomas.

Non-functioning pituitary adenomas (NFPAs) are a highly heterogeneous group and often show invasion, but few studies have explored the invasion mechanism and biomarkers for specific subtypes. This study was designed to describe the role of HIF1α and its downstream genes in specific subtypes of NFPAs. Specimens were classified into two subtypes of NFPAs: 46 null cell adenomas (28 invasive and 18 noninvasive) and 46 oncocytomas (11 invasive and 35 noninvasive).